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123  Urolithiasis in Small Animals  1135

                                                                  transducer, and found that ultrasonography may be
  VetBooks.ir                                                     more sensitive than survey and contrast cystography
                                                                  for detection of urocystoliths, with false‐negative rates
                                                                  of 6%.
                                                                   Ultrasonography allows simultaneous evaluation of
                                                                  the upper urinary tract for nephroliths and ureteroliths.
                                                                  Therefore, radiography combined with ultrasonogra­
                                                                  phy  are preferred over contrast radiography alone.
                                                                  Ultrasound can detect upper urinary tract obstruction
                                                                  that is characterized by renal pelvis dilation >13 mm.
                                                                  However, pelvis dilation can be iatrogenic (diuresis) or
                                                                  secondary to different diseases such as chronic kidney
                                                                  disease or pyelonephritis. Although a renal pelvis
                                                                  >13 mm may indicate ureteral obstruction, the absence
                                                                  of dilated renal pelvis does not rule out an upper urinary
                                                                  tract obstruction. The combination of proximal ureteral
                                                                  dilation and normal kidney pelvis diameter can be asso­
               Figure 123.12  Abdominal radiographs (lateral view) showing   ciated with ureteral obstruction in cats. In a recent study,
               bladder and urethral stones in a dog. Source: Courtesy of   25% of cats with confirmed ureteral obstruction had a
               Stephanie Nykamp, Radiologist, Ontario Veterinary College.
                                                                  renal pelvis <13 mm but a proximal ureteral dilation. In
                                                                  25% of cats with ureteral obstruction, ureteropyelog­
                                                                  raphy is necessary to determine the cause of the
                                                                  obstruction.

                                                                  Computed Tomography
                                                                  Determination of urolith composition using computed
                                                                  tomographic (CT) peak attenuation measurement has
                                                                  been described  in vitro. In humans, this technique is
                                                                  preferentially used in order to detect uroliths and also to
                                                                  predict their composition. CT may be more specific for
                                                                  ureteral  calculi than  either radiography  and/or  ultra­
                                                                  sonography in cats.
               Figure 123.13  Double‐contrast cystography (lateral view) in a
               dog showing multiple, various sized filling defects centrally in the   Educated Guess
               contrast pool indicative of bladder stones. Source: Courtesy of
               Dr Stephanie Nykamp, Radiologist, Ontario Veterinary College.  Determining the type of urolith based on imaging stud­
                                                                  ies alone is very risky. This type of “guesstimate” of uro­
               Ultrasonography                                    lith composition based on the radiolucency of a stone
               Ultrasonography is a cost‐effective tool in the diagno­  and its shape can lead the clinician to misdiagnosis
               sis of urolithiasis but it may overlook some important   (Figure 123.14). In certain scenarios the chemical com­
               aspects of the stones that can help the clinician predict   position of uroliths may be predicted based on patient
               the nature of the uroliths, such as surface contour and   signalment, in combination with the results of urinalysis,
               shape. One limitation of  ultrasound is that it  often   urine culture, and radiographs. However, it must be
               overestimates urolith size, so radiographs should be   understood that this technique can lead to error and is
               used for determining size when possible. Ultrasound is   not advised as the best method of urolith identification.
               also less reliable than radiography for predicting the   In situations where uroliths are not available for analysis
               number of stones and their location. Finally, ultra­  or are pending analysis, the guesstimate may need to be
               sound only provides evaluation of the most proximal   used; however, communication to clients that errors may
               portion of the urethra and therefore cannot replace   be made with this technique and verification of stone
               radiography.                                       type (when practical and possible) are ideal. Unfortunately,
                 Ultrasonographic examination can detect radiopaque   this verification cannot be made until stone analysis
               and radiolucent uroliths. One study compared survey   occurs. For example, the clinician can make an educated
               and contrast radiographs, pneumocystography, double‐  guess as to the likelihood that a given stone is com­
               contrast cystography, and ultrasound using a 7.5 MHz   posed of struvite based on finding a urease‐positive
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