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140  Cancer of the Airway and Lung  1281

               Table 140.1  Prognostic factors and associated median survival times for dogs with lung tumors
  VetBooks.ir                                                                    Median survival time



                Prognostic marker for dogs with lung tumors        Present                   Absent

                Lymph node metastasis                              1 month                           15 months
                Microscopic disease following surgery              1 month                           11 months
                Metastases                                         <1 month                          15 months
                Clinical signs at diagnosis                        8 months                          18.1 months
                Median survival time
                Histologic grade
                Grade 1                                            26.3 months
                Grade 2                                            8.3 months
                Grade 3                                            <1 month

                Histologic type
                Squamous cell carcinoma                            8 months
                Adenocarcinoma                                     19 months
                Solitary tumor                                     26 months
                Multifocal tumors                                  7 months
                Tumors invading into surrounding tissue            3 months



                 Further Reading

               Ambrust LJ, Biller DS, Chun R, Garrett LD, Sanderson   Hahn KA, McEntee MF. Primary lung tumors in cats: 86
                 MW. Comparison of three‐view thoracic radiography   cases (1979–1994). J Am Vet Med Assoc 1997; 211(10):
                 and computed tomography for detection of pulmonary   1257–60.
                 nodules in dogs with neoplasia. J Am Vet Med Assoc   Norris CR, Griffey SM, Samii VF, et al. Comparison of results of
                 2012; 240(9): 1088–94.                             thoracic radiography, cytologic evaluation of bronchoavleolar
               Carlisle CH, Biery DN, Thrall DE. Tracheal and       lavage fluid, and histologic evaluation of lung specimens in
                 laryngeal tumors in the dog and cat: literature review   dogs with respiratory tract disease: 16 cases (1996–2000).
                 and 13 additional patients. Vet Radiol 1991; 32(5):   J Am Vet Med Assoc 2001; 218(9): 1456–61.
                 229–35.                                          Poirier VJ, Burgess KE, Adams WM, et al. Toxicity,
               Hahn FF, Muggenburg BA, Griffith WC. Primary lung    dosage, and efficacy of vinorelbine (Navelbine) in dogs
                 neoplasia in a beagle colony. Vet Pathol 1996; 33(6):   with spontaneous neoplasia. J Vet Intern Med 2004;
                 633–8.                                             18(4): 536–9.
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