Page 1400 - Clinical Small Animal Internal Medicine

1338 Section 11 Oncologic Disease

Vaccine‐associated sarcomas are graded from I (least) metastasis. In cats, it appears that completeness of exci-
VetBooks.ir to III (most aggressive) depending on mitotic index, dif- sion is one of the most important prognostic factors.
Hence, it is very important that everything is done to
ferentiation, and necrosis. Approximately 15–24% of
vaccine‐associated sarcomas will metastasize to the
margins when recommending treatment for these
lungs or other sites, and evidence has suggested that a ensure the greatest possibility of obtaining complete
higher grade is associated with an increased risk of tumors in cats.

Further Reading

Dennis M, McSporran K, Bacon N, Schulman F, Foster R, soft tissue sarcomas. J Vet Intern Med 2008; 22(6):
Powers B. Prognostic factors for cutaneous and 1373–9.
subcutaneous soft tissue sarcomas in dogs. Vet Pathol Kobayashi T, Hauck M, Dodge R, et al. Preoperative
2011; 48(1): 73–84. radiotherapy for vaccine associated sarcoma in 92 cats.
Ehrhart N. Soft‐tissue sarcomas in dogs: a review. J Am Vet Radiol Ultrasound 2002; 43(5): 473–9.
Anim Hosp Assoc 2005; 41(4): 241–6. Mayer M, Treuil P, LaRue S. Radiotherapy and surgery for
Elmslie R, Glawe P, Dow S. Metronomic therapy with feline soft tissue sarcoma. Vet Radiol Ultrasound 2009;
cyclophosphamide and piroxicam effectively delays 50(6): 669–72.
tumor recurrence in dogs with incompletely resected