Page 1447 - Clinical Small Animal Internal Medicine
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157  Approach to the Patient with Dermatologic Disease  1385


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               Figure 157.7  Epidermal collarette – these are formed from the
               remnants of a pustule or vesicle after the roof has been lost, or
               caused by a point source of inflammation, as seen with papules.
               DDx – superficial bacterial folliculitis most commonly. Fungal
               infection, immune‐mediated dermatoses, contact hypersensitivity,
               and insect bite reaction are less common causes. Photograph
               illustrates an epidermal collarette associated with superficial
               bacterial folliculitis.
                                                                  Figure 157.9  Erosion/ulceration – develop due to rapid death
                                                                  and/or loss of keratinocytes as a consequence of self‐inflicted
                                                                  trauma or inflammation. An ulcer denotes a deep pathologic
                                                                  process. DDx – autoimmune dermatoses, erythema multiforme,
                                                                  toxic epidermal necrolysis, drug reaction, SND, feline indolent
                                                                  ulcer, deep pyoderma, deep mycoses, vasculitis, neoplasia,
                                                                  chemical/thermal burn. Photograph illustrates an ulcer on the
                                                                  lateral aspect of the thorax of a dog with a cutaneous adverse
                                                                  drug reaction secondary to itraconazole therapy.













               Figure 157.8  Excoriation – these lesions are self‐induced and
               occur secondary to scratching, biting, and/or rubbing. Usually
               result from pruritus. Photograph illustrates excoriations and
               erosions due to scratching and licking on the lateral aspect of the
               thorax of a cat with adverse food reaction.

               therapeutic trials, biopsy and histopathology, and tests
               of noncutaneous organs.
                                                                  Figure 157.10  Fissure – lesions may be caused by underlying
                                                                  disease or injury when the skin is thick and then subjected to
               Screening Tests                                    sudden swelling. DDx – SND, canine distemper, zinc‐responsive
               Cytology                                           dermatosis, chronic skin diseases, and keratinization disorders.
               Cytology is a powerful tool, allowing one to quickly deter-  Photograph illustrates fissures on the metacarpal pawpad of a
                                                                  dog with SND.
               mine whether a lesion is sterile or if infectious organisms
               and inflammation are present. It allows the clinician to pre-
               sumptively diagnose a patient with autoimmune diseases,     cutaneous lymphoma and mast cell tumors. Cytology can
               such as pemphigus, when acantholytic cells are observed.   be performed in a number of ways depending on the area
               Neoplastic processes may also be identified, such as   and the condition of the skin being sampled.
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