Page 898 - Clinical Small Animal Internal Medicine
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836  Section 9  Infectious Disease

            and risk factors can prevent implementation of success-  of the outbreak, individuals may have a good chance to
  VetBooks.ir  ful interventions. This may lead to treatment failure and   recover from infection. Treatment options may be cost‐
                                                              prohibitive for some owners or treatment may be refused
            continued spread of the disease.
             Observational studies facilitate comparisons between
                                                              of disease if owners follow strict isolation and quarantine
            affected and nonaffected populations (cases and con-  for various reasons. This may have little effect on spread
            trols) with measures of association. Retrospective case–  protocols. Unfortunately, some owners may refuse
            control studies are relatively quick and easy to perform,     quarantine and isolation procedures designed to stop
            but may be hampered by incomplete or imperfect    the  spread to naive animals and veterinarians have
            data collection or availability in medical records. Odds   few options to mandate such procedures without a risk
            ratios can be calculated to identify risk factors for   to public health or safety. In these situations, effective
              disease and support hypothesized control or prevention   and compassionate communication of risk may help
            interventions.                                    increase compliance and mitigate risk of further spread
             Prospective cohort studies are more expensive and   of disease.
            time consuming compared to case–control studies, but
            provide incidence data which lead to more accurate
              estimates of risk through relative risk calculations. Their     Step 6: Communicate Findings
            prospective nature provides an opportunity for more   For public health outbreak investigations, communica-
            complete data collection in both affected and nonaf-  tion of findings includes informing the healthcare com-
            fected populations which would not be available in   munity of the “who, what, where, when, why, and how”
              historical medical records. As with case–control studies,   of the outbreak. This can increase awareness of the
            cohort studies also identify potential risk factors for   potential for continued spread of the disease and
              disease and support interventions to reduce or prevent   allow implementation of preventive measures and early
            further disease spread.
                                                              detection of the disease in new populations.
                                                                If the disease outbreak under investigation has a public
            Step 5: Implement Control and Prevention          health implication, and local public health officials were
            Measures                                          not part of the investigation process, it is important to
                                                              communicate relevant findings to the local public health
            Descriptive epidemiologic data from epidemic curves   department. Findings should include date of onset and
            and risk factors determined from observational studies   conclusion (if outbreak has ended), case definition/
            must be carefully analyzed to determine what interven-  diagnosis, populations  affected,  epidemic  curves, and
            tions will provide the greatest benefit and likelihood of   outcomes of control and prevention measures. This
            success. Measures must be directed at controlling the   information should also be shared with other veterinari-
            current outbreak through treatment, if possible, and   ans in the practice area so results of the investigation can
              preventing continued spread of the disease into naive   be used to control and prevent disease in the larger
            animals in the population.                          population of animals in the community.
             In small animal clinical practice, these actions can
                                                                Findings from new or novel disease outbreaks should
              provide significant challenges not encountered in pop-  also be communicated to the larger veterinary audi-
            ulations under ownership or control of relatively few   ence through publication in journals or presentations
            parties.  When  a  population  of  animals  has  a  single   at    continuing education functions. Increased aware-
            owner, the potential loss of a few animals is mitigated   ness may prevent further outbreaks or mitigate the
            by the benefits of disease prevention in the larger   effects of outbreaks if they spread to new companion
              population. Sacrificing a few animals for diagnostic   animal populations.
            procedures or to prevent further disease spread often
            makes economic sense. With companion animals, the
            value of individual animals does not lie just in dollars
            and cents, but also in an unquantifiable emotional value     Conclusion
            as a member of the family. The good of the population
            does not necessarily override the value of the individ-  Epidemiology is an integral part of the daily practice of
            ual, creating difficult choices for mitigating disease at a   veterinary medicine whether veterinarians realize it or
            population level.                                 not. Tools and techniques for disease monitoring and
             Recommendations for treating individual animals   surveillance and outbreak investigations are readily
            are  likely to be accepted and, depending on the cause   available and can add to a veterinarian’s epidemiology
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