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21.2 Contrast  adiography  339
               has been made. The stomach should be empty or contain   Segmental contractions are more obvious in cats than in
               only a coating of barium at this point. Although barium   dogs  and  the  duodenum  may  have  a  “string  of  pearls”
               reaches the colon, the study should not be relied upon for   appearance  (Figure  21.7).  Lymphoid  follicles  (Peyer’s
               diagnosis  of  colonic  disease.  There  may  be  remaining   patches) appear similar to ulcers but are more symmetric,
               material in the colon and the colon may not be adequately   causing them to be referred to as “pseudo‐ulcers.” Barium
               coated or distended.                               will be in the colon at 30–60 minutes and by 90 minutes,
                 Problems that result in a poor study include poor prepa-  most of the barium will be in the colon. The cecum is non-
               ration,  inadequate  dosage  and  failure  to  expose  enough   sacculated and has the shape of a comma. Normally the GI
               films  to  allow  recognition  of  persistence  of  lesions.  The   tract is continuously moving. True anatomic abnormalities
               most  common  complication  is  aspiration  of  barium.   will persist from one film to another. Repeatability helps to
               Material  in  the  trachea  and  main  bronchi  is  usually   confirm that a suspected lesion is real and is not secondary
               coughed  up  but  barium  that  reaches  the  alveoli  will  be   to a temporary contraction.
               retained. Because barium is inert and nonirritating, aspira-  Unless  a  foreign  body  or  mass  is  identified,  most  GI
               tion  of  a  small  amount  of  barium  is  generally  not  life   series do not yield a specific diagnosis but anatomic disease
               threatening and adverse clinical signs are usually not seen.   may  be  identified  and  the  extent,  location,  and  nature
               The barium will be walled off and will remain visible on   (mucosal or infiltrative, focal or diffuse, obstructive or non-
               radiographs  years  later.  Aspiration  of  a  large  amount  of   obstructive) of lesions might be noted.
               barium such as that delivered by a gastrointestinal tube is
               deadly.
                 Occasionally, administration of barium is made difficult   21.2.6  Contrast Studies with Iodinated
               by an excited, frightened, or intractable patient. Sympathetic   Contrast Media
               stimulation can alter GI motility. If sedation becomes nec-  Iodinated contrast media should be used for management
               essary, drugs should be used that do not have a strong effect   of PEG tubes or if perforation is suspected because barium
               on GI motility. Ketamine/diazepam has been suggested.  can cause a severe granulomatous response in the perito-
                                                                  neal cavity [4]. It is also useful for esophagography if the
                                                                  integrity of the esophagus is in question (Figure 21.8). For
               21.2.5  Normal Gastrointestinal Series
                                                                  cats,  nonionic  iodinated  contrast  is  preferred  over  ionic
               Gravity should be relied on to fill various portions of the   contrast. Iodinated contrast is not used for routine studies
               stomach (Figure 21.7). In right lateral recumbency, there   because it does not coat the mucosa as well as barium and
               will be maximum filling of the pylorus with barium while   has a slightly blurred appearance compared to barium. In
               some gas may be seen in the fundus. In left lateral recum-  determining the amount of contrast to administer, both the
               bency, gas may be seen in the pylorus while barium runs by   amount  of  iodine  per  body  weight  and  the  total  volume
               gravity  into  the  fundus.  For  the  dorsoventral  projection   need to be considered. First, calculate the amount of iodine
               (sternal  recumbency),  the  body  of  the  stomach  will  be   as 600–800 mg iodine per kg. Calculate the total volume as
                 closest to the cassette and will have maximal filling with   10 mL per kg and dilute the iodine with sterile water to the
               barium.  For  the  ventrodorsal  projection  (dorsal  recum-  required volume [3]. The contrast is then given orally.
               bency),  gas  may  be  present  in  the  body  of  the  stomach.
               Most cats will have a J‐shaped appearance with the pylorus   21.2.7  Pneumogastrogram
               on or to the right of the midline. A few cats will have a
               stomach that extends further across to the right side.  A pneumogastrogram is a negative contrast study of the
                 Gastric emptying and intestinal transit are faster in cats   stomach performed by passing a nasogastric tube into the
               than  dogs,  necessitating  more  frequent  exposures  over  a   stomach  and  inflating  the  stomach  to  slight‐to‐moderate
               shorter  period  of  time.  All  four  projections  should  be   degree. The procedure can be done to screen for a foreign
               obtained immediately after administration of barium con-  body  or  to  determine  the  position  of  the  stomach.
               trast. Right lateral and ventrodorsal projections should be   Preparation is usually minimal prior to the procedure.
               made at 15, 30, and 60 minutes after the start of the proce-
               dure. Subsequent exposures should be made at 30‐minute
               intervals until the study is complete.             21.2.8  Double-Contrast Gastrogram
                 As  barium  proceeds  through  the  small  intestine,  the   A double‐contrast study requires preparation similar to that
                 contrast column should be continuous, sometimes referred   of a barium series because the stomach should be empty to
               to  as  a  ribbon.  Intestinal  villi  cause  the  margins  of  the   allow  for  coating  of  the  gastric  mucosa  with  barium.
                 contrast  column  to  be  slightly  irregular  or  “feathered.”   10–20 mL  of  barium  is  administered  before  inflating  the
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