Page 272 - Veterinary Immunology, 10th Edition
P. 272
B Cells, 96
VetBooks.ir Other Cells, 96
Antigen Processing, 96
MHC Class II Pathway, 96
MHC Class I Pathway, 97
Cross-Priming, 99
Histiocytosis and Histiocytomas, 99
LEARNING OBJECTIVES
After reading this chapter, you should be able to:
• Explain the importance of antigen processing in the development of adaptive
immunity.
• Compare the processing of exogenous and endogenous antigens.
• Describe the characteristic properties of dendritic cells (DCs), their
subpopulations, and their origins.
• Recognize that DCs, macrophages, and B cells are the major cell types that
capture and process foreign antigens.
• Describe why DCs are the most efficient of these antigen-processing cells.
• Explain how immature DCs are especially equipped to capture and process
antigens.
• Explain how mature DCs are highly effective in presenting these processed
antigens to T cells.
• Describe how macrophages also act as antigen-presenting cells, and why they
are much less efficient than DCs.
• Explain how B cells can also act as antigen-presenting cells and are especially
effective during secondary immune responses.
• Define dendritic cells, antigen processing, antigen presentation, Langerhans
cells, exogenous antigen, endogenous antigen, and proteasome.
• Compare dendritic cells and macrophages.
• Describe the major histocompatibility complex (MHC) class I pathway of
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