Page 37 - Veterinary Immunology, 10th Edition
P. 37

VetBooks.ir



































                            FIG. 1.5  A simple flow diagram showing the essential features of
                               the humoral and cell-mediated adaptive immune responses.


                  Because antibodies do not work inside cells, immunity to
               intracellular invaders is the function of T cells. The T cells can
               destroy infected or abnormal cells. This type of response is

               therefore called the “cell-mediated immune response.” There are
               three major types of T cell. One is responsible for killing abnormal
               cells and so consists of cytotoxic T cells. Another type is responsible
               for providing the signals that activate the adaptive immune

               responses and hence are called helper T cells. The third cell type
               regulates immune responses and so are called regulatory T cells.
               Most importantly, adaptive immune responses generate long-lived
               populations of memory T and B cells that ensure that this immunity

               persists for a long time, perhaps even as long as the animal's
               lifetime.


               Antibody-Mediated Immunity

               Soon after it was discovered that animals could be made immune to

               infectious agents by vaccination, (Chapter 24) it was recognized
               that the substances that provided this immunity could be found in
               blood serum. For example, if blood is taken from an immune horse




                                                          37
   32   33   34   35   36   37   38   39   40   41   42