Page 913 - Veterinary Immunology, 10th Edition

Immunity to Arthropods, 322
VetBooks.ir Demodectic Mange, 322

Flea-Bite Dermatitis, 322

Tick Infestation, 322

Hypoderma Infestation, 323

LEARNING OBJECTIVES

After reading this chapter, you should be able to:

• Understand how parasites are able to evade their host's immune response for at
least sufficient time for the parasite to reproduce.

• Explain how, in general, antibody-mediated immune responses protect against
extracellular protozoa, whereas cell-mediated responses control intracellular
protozoa.

• Explain how trypanosomes undergo sequential antigenic variation.
• Discuss the availability and effectiveness of vaccination against protozoan
diseases.

• Describe the complex strategies employed by protozoan parasites to ensure
their survival in the face of an animal's immune response.
• Explain how helminth parasites have a unique ability to trigger type 2 immune

responses.
• Discuss the different forms of immune response required to combat intestinal
versus tissue helminths.

• Explain how eosinophils are uniquely able to damage and kill helminths.
• Describe the mechanisms employed by helminths to evade their host's immune

responses.
• Discuss the availability of vaccines against parasitic helminths.
• Discuss the role of type 2 responses in immunity to parasitic arthropods such as
ticks and biting flies.

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