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The Ādam Paradox Hypothesis 242
Phase II (5–10 Years): Expansion and Integration
Goals: Broaden scope, integrate data streams, and attempt first falsification tests.
Broaden the scope of research, integrate genomic, archaeological, and
neuroscience data streams, and conduct the first serious falsification tests of the
Adam Paradox Hypothesis (APH).
Genomics
What to Do
1. Large-scale sequencing projects targeting ignition loci across diverse
populations.
Moving from pilot studies (Phase I) to massive data collection.
This means sequencing thousands of genomes worldwide — not only
African, but also Eurasian, Oceanian, and Indigenous populations.
Focus remains on ignition-linked loci (HAR1, FOXP2, SRGAP2C,
enhancers) to see how widespread these sweeps are.
2. Develop global haplotype networks to test for synchrony of sweeps
near ~70kya.
Instead of analyzing populations in isolation, researchers build a worldwide
genetic map of haplotypes.
This shows whether selective sweeps occurred synchronously across
populations, consistent with a rapid ignition event, or whether they appear
gradually in different regions.
Tools
Large-scale sequencing platforms (e.g., Illumina NovaSeq, Oxford
Nanopore, long-read technologies) for thousands of genomes across
multiple continents.
Global haplotype networks (more advanced software, integrating data
across populations to test synchrony).
Cloud-based genome databases & AI analysis pipelines to handle terabytes
of genomic data, something not feasible in Phase I.