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                   1.  Food Additive Petition )FAP(             16.The White House Emerging Technologies Inter-
                  2.  https://www.fda.gov/science-research/nano-  agency Policy Coordination Committee
                 technology-programs-fda/nanotechnology-guid-   17.See http://www.nano.gov/
                 ance-documents                                 18.Nanoscale Science, Engineering and Technology
                  3. https://www.fda.gov/ScienceResearch/Special-     19.Nanotechnology Environmental and Health
                 Topics/Nanotechnology/ucm273325.htm           Implications
                  4. Sprague-Dawley rats                       20. See: https://us-eu.org/communities-of-re-
                  5.Collaborative Opportunities for Research Excel-  search
                 lence in Science                               21.Communities of Research
                  6. Listeria                                   22.National Institute of Standards and Technology
                  7. Negative treatment response controls includes   23. Joint Research Center
                  the vehicle control group, in which animals receive   24. office of Science and Technology Policy
                 treatment with the vehicle in which the experimen-   25. Executive Office of the President
                  tal substance is dissolved or suspended, and the    26.See: https://ncl.cancer.gov/resources/as-
                  inactive treatment control group, in which animals  say-cascade-protocols
                 receive treatment with an inactive substance relat-    27.Consumer Protection Safety Commission )CPSC(
                 ed to the experimental ...                      28.The Defense Advanced Research Projects
                   8.A positive control group is a control group that  Agency )DARPA(
                  is not exposed to the experimental treatment but   29.The Defense Threat Reduction Agency )DTRA(
                  that is exposed to some other treatment that is    30.The United States Pharmacopeia )USP(
                  known to produce the expected effect. These sorts   31. Dosage Forms
                  of controls are particularly useful for validating the    32.Arkansas Universities
                 experimental procedure.                        33.The Arkansas Research Alliance
                   9.Khan S et al. Investigating the susceptibility    34.The Winthrop Rockefeller Institute
                  of mice to a bacterial challenge after intravenous     35.The International Pharmaceutical Regulators
                  exposure to durable nanoparticles. Nanomedicine  Programme )IPRP(
                 12)17( 2017.                                    36.The Global Summit in Regulatory Science
                  10. National Nanotechnology Initiative       )GSRS(
                  11.https://www.nano.gov/sites/default/files/    37.Bethesda, Maryland
                 pub_resource/2016-nni-strategic-plan.pdf       38.Standards Development Organizations )SDOs(
                  12.Riaz Ahmed KB et al. Silver nanoparticles: Sig-    39.The International Organization for Standardiza-
                  nificance of physicochemical properties and in vitro  tion Technical Committee 229 Nanotechnologies
                  studies in toxicological risk assessment. Toxicology    40. American Society for Testing and Materials
                 In Vitro 38, 2017                             Committee E56 on Nanotechnology )ASTM E56(
                  13. The Nanotechnology Characterization Labora-     41.The Organization for Economic Cooperation and
                 tory )NCL(                                    Development
                  14.The National Cancer Institute )NCI(        42.The International Life Sciences Institute
                  15.The National Institute of Standards and Tech-    43.The Nanotechnology Standards Subcommittee
                 nology )NIST(                                  44.Cryo-Transmission Electron Microscopy )Cryo-









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