Page 107 - The Manga Guide to Biochemistry

Next up are Phospholipids have a
phospholipids! structure in which one
of the three fatty acids
• Phospholipid
of a neutral lipid is
replaced by a chemical

compound containing
phosphoric acid.

One of these things
is not like the others.

By the way, Kumi, Remember
we already talked
about phospholipids when we
once, Remember?
talked about
Umm...not the cell
really...
membrane?

Guuuh

It consists mainly
of phospholipids!

Phospholipids have phospholipid phosphoric hydrophilic
a property called acid hydrophobic

amphipathicity. Fatty acid

The two fatty acid parts
are hydrophobic, while the

chemical compound part
containing phosphoric
acid is hydrophilic.

Because of this, a two-layer
membrane can be created with
the hydrophobic part facing

inward and the hydrophilic
part facing outward.

hydrophilic phospho­
lipid

Hydrophobic Variable
polar
* A phospholipid can have a variable polar group head*
as its head. A phospholipid that is based on
glycerol is called a glycerophospholipid. Hydrophilic means it
sphingophospholipids have sphingosine heads. readily mixes with water.
Hydrophobic means it does
not readily mix with water.
Amphipathic means that it's
made from both of these

kinds of substances.