Page 118 - The Manga Guide to Biochemistry
P. 118

Blood                                          Macrophage
vessel
                                                                                    Oxidized LDL
  wall                                                                               is eaten by
                                                                                  macrophages.

                                          LDL

                                                                         Foam cells accumulate,
                                                                     smooth muscle cells grow

                                                                       rapidly, and blood vessel
                                                                              walls get thicker!

                                                    Foam cells

               bulge                      Stretch

                                                                  Misshapen smooth muscle cells

               Wow, that artery is even more clogged than the pipes in my bathtub. But at least
               some hair in the drain won’t kill me!

               Don’t be so sure. The clog in my tub practically has a mind of its own. It’s a real
               jungle down there!

               Whoa, gross! TMI, Nemoto!

               Er...sorry. Anyway, you can see some of the illnesses that arteriosclerosis can cause
               below.

               Brain                      Cerebral infarction (stroke)
                                                Cerebral hemorrhage

               Heart                           Angina pectoris
                                          Myocardial infarction

104 Chapter 3
   113   114   115   116   117   118   119   120   121   122   123