Page 44 - Medicinal Chemistry Self Assessment
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1.9 Aripiprazole 33
6. Shown below are three known metabolites of aripiprazole. Identify the metabolic transformations that
6. Shown below are three known metabolites of aripiprazole. Identify the metabolic transformations
would be required to form each of the metabolites. For each metabolic transformation, indicate if it is
that would be required to form each of the metabolites. For each metabolic transformation, indicate
a phase I transformation or a phase II transformation.
if it is a phase I transformation or a phase II transformation.
O
H
N
Cl Cl O
H O N N
Metabolite A
O
H
N
Cl Cl O
OH
N N
Metabolite B
O
H
N
Cl Cl O
OH
N NH H O
O
Metabolite C
Answers can be found in Section 2.9 [this will be linked to section 2.9 title]
