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cawangan
                                                                                                                                                                                                                                        Kelantan
                                                                                                                                                                                                                                      K242/17
                                                                                                                                                                                                                 NAME: SITI NUR AFIZAH BINTI AZMAN
                                                                                                                                                                                                                 NAME: SITI NUR AFIZAH BINTI AZMAN
                                                                                                                                                                                                                 NAME: SITI NUR AFIZAH BINTI AZMAN
                                                                                                                                                                                                                 SUPERVISOR: FARAHANIE BINTI FAUZIE
                                                                                                                                                                                                                 SUPERVISOR: FARAHANIE BINTI FAUZIE
                                                                                                                                                                                                                 SUPERVISOR: FARAHANIE BINTI FAUZIE
                                                                                                    ABSTRACT
                                                                                                                                                                  osquito
               study
        This study presents a mathematical model of the Sterile Insect Technique (SIT), formulated to simulate mosquito population dynamics
                                                                                                                                                                              population
                                                                                 Sterile
                                                                                                                                                               m
                                                             model
                                                                                                    Technique
        This This  study  presents   a  mathematical         model     of  the  Sterile    Insect   Technique       (SIT),  formulated        to  simulate     m  osquito     population       dynamics
                                                                                                                            formulated
                                                                                                                                                  simulate
                                                                       of
                                        mathematical
                                                                                                                                              to
                                                                                                                    (SIT),
                       presents
                                                                                           Insect
                                                                           the
                                     a
                                                                                                                                                                                               dynamics
                                                                                     a
                                                                                        Fehlberg
                        with
                                the
                                                                                                                                                                                     Excel
                                                                                                                                                                                              to
                                     Zika
                                                                                                                  (RKF45),
                                                                                                                                                                                                  analyze
                                                                     Runge-Kutt
                                                                                                     method
                                                                                                                                                                                 in
                                                                                                                                                     numerica
                                                                                                                                    model
                                                                                                                              the
        associated with the Zika virus. Using the Runge-Kutta Fehlberg method (RKF45), the model was numerically solved in Excel to analyze
                                                      Using
        associated associated  with  the  Zika  virus.  Using  the  Runge-Kutt       a  Fehlberg     method       (RKF45),    the   model     was    numerica      lly  solved   in  Excel    to  analyze
                                                                                                                                              was
                                                                                                                                                                   lly
                                                                                                                                                                       solved
                                             virus.
                                                               the
                                     across
                                                     compartments.
                                                                                                              DTM-based
                                                                                                                                                                                           and
                                                                                                                                                   used
                         changes
                                                                                                                                                                                                 validate
        population population  changes  across  six  compartments.          A  previously      published      DTM-based        solution     was    used   to  benchmark         trends    and    validate
                                                                                                                                            was
                                                                                               published
        population changes across six compartments. A previously published DTM-based solution was used to benchmark trends and validate
                                                                                                                               solution
                                                                                                                                                           to
                                                six
                                                                                                                                                               benchmark
                                                                               previously
                                                                            A
                                                                                                                                                                                trends
                                                                                                                                              SIT
                                              simulation
                                                                                                     this
                                                                                                                                                                           insights
                                                                                                                                     using
                                                                                                           theoretical
                                                                                                                                                   model
                                                                                                                                                                                       that
                                                                                                                                                             provides
                                                                                                                            study
                                                               and
                                                                                                                                                                                              can
                                                                                      variation,
        RKF45 reliability. Through simulation and parameter variation, this theoretical study using SIT model provides insights that can assist
                                 Through
                                                                     parameter
                 reliability.
                                                                                                                                                                                                     assist
        RKF45 RKF45  reliability.  Through    simulation       and   parameter           variation,  this  theoretical      study    using    SIT  model     provides      insights    that   can   assist
        biologists in designing future field experiments for mosquito control strategies.biologists in designing future field experiments for mosquito control strategies.
        biologists in designing future field experiments for mosquito control strategies.
                                 PROBLEM STATEMENT                                                                                   OBJECTIVE
           The  Sterile  Insect  Technology  (SIT)  has  emerged  as  a  promising                                                                                                                     METHOD
           theoretical  approach  to  help  suppress  mosquito  populations                                             Apply the RKF45 method to solve
           associated  with  the  spread  of  Zika  virus  (ZIKV).  Through                                             the SIT model;
           mathematical  modeling,  SIT  can  guide  biologists  in  evaluating                                         Utilize the DTM-based solution for                                                   Start
           population  dynamics  before  conducting  experimental  field                                                validation;
           strategies. This study presents a theoretical framework using a                                              Analyze the effects of varying
           system of nonlinear differential equations to simulate mosquito                                              mating parameters (β₁ and β₂) on                                           Define SIT Model Equation
           dynamics under SIT conditions. By analyzing numerical outputs,                                               the model outcomes.                                                       (ODE system from literature)
           the  model  supports  biologists  in  designing  and  refining
           experimental strategies for mosquito population suppression.
                                                                                                                                                                                                Specify the Initial Condition and
                                                                                                                                                                                                       Parameter Values
                                                                   IMPLEMENTATION
                                                                                                                                                                                         Solve the Same Problem using RKF45 with the
                                                                                                                                                                                           same Initial Condition via Microsoft Excel
                                                                                                                                                                                                (fixed h = 0.1 and from t = 0.1 to 1.0)
                                                                                                                                                                                      Use DTM-Based Equation from previous research
                                                                     Variable description                                                                                                            as a benchmark only
                                                                                                                                                                                           (Substitute t-value manually using excel)
                                                                                                                   DTM-based solution evaluation by substituting t-values into the
                                                                                                                   existing polynomial equation. Used as a benchmark to validate
                                                                                                                                    RKF45 simulation results.                          Simulate RKF45 Output for Parameter Variations
                                                                                                                                                                                             (Change β₁ = {0.5,0.6,0.8,0.9} and β₂ =
                                                                                                                                                                                                         {0.1,0.2,0.4,0.5})
                                                                                                                                                                                              Graph Result and Interpret Dynamic
                                                               RKF45 Butcher Tableau Formula                         Manual RKF45 calculation in Excel for A(t), showing all                   Across 6 Mosquito Compartments
                                                                                                                                                   ,

                                                                                                                   intermediate slope values k1 to k6  and the updated value
           Parameter Table and Initial Conditions
                                                                                                                                                                                                              End
                                                                                          RESULTS & DISCUSSION
         a) Mosquito Population Dynamics in SIT Model Simulated Using RKF45 : Compartment trends for A(t), FM(t), MM(t), FNM(t), FSM(t), and Ms(t) over the time interval t = 0.0
                                                                                                       to t = 1.0 using fixed step size.
                                                               A steep decline over time indicates
                                                              transition of females into reproductive
                                                              compartments or natural death, typical in
                                                                  early-stage SIT dynamics.
                                                                                                                                                               Increase from sterile male mating, do
                                                                                                                                                                 not contribute to hatch rates.
                                                                           Population increases with active mating
                                                                               rates and egg production.
                                                              The aquatic population shows rapid initial
                                                             growth due to oviposition before stabilizing
                                                              near equilibrium, reflecting environmental
                                                                capacity limits in the SIT model.
                                                                                                                                                               Sterile male levels remain high due to release
                                                                                                                                                               strategies, maintaining suppression pressure
                                                                                                                                                                and influencing the proportions of sterile
                                                                                                                                                                       offspring.
                                                                            The wild male population remains relatively
                                                                            stable, providing mating competition against
                                                                            released sterile males—critical in the SIT mating
                                                                                    dynamic.



      b) Sensitivity Simulation for Mating Parameters β₁ and β₂ : Showing how changes in mating rates B₁ and B₂ influence reproductive and non-reproductive female populations in
                                                                               the SIT model (β₁: 0.5,0.6,0.7,0.8,0.9  and β₂: 0.1,0.2,0.3,0.4,0.5).






















                                                                Higher β₁ raises reproductive females, while higher β₂ enhance sterile ones




                                                   CONCLUSION & RECOMMENDATIONCONCLUSION & RECOMMENDATION
                                                   CONCLUSION & RECOMMENDATION


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                 method produced results consistent with previous literature, and the sensitivity analysis supported the effectiveness of sterile male releases in suppressing
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                                Expand parameter variation to include oviposition and aquatic death rates for deeper analysis.
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                                Explore other numerical methods such as LADM or Laplace Transform for performance comparison.                                 . .

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