Page 306 - Pharmacognosy 2 PG303
P. 306

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

              in Central Africa, forming forests of considerable extent. The best gum is produced
              near Kordofan from trees specially cultivated and worked for gum.

               Collection and Preparation
                     The trees are kept properly pruned from dead wood and the lowest branches
              are removed. The formation of gum is greatly increased by wounding the stems and
              is apparently taken place first in the young phloem and cambium. Towards the end
              of November and again in February and March the taper visits trees about six or
              seven years old and drives the small blade of a long-handled axe just under the bark
              of the stem and large branches without injuring the cambium. By twisting the axe
              and pulling it back he leaves two ends. One of these he pulls up and the other down
              and so removes a strip of bark 0.5-1.0 metre long. About 3-6 weeks afterwards the
              gum which forms in tears near the lower end of the wound is collected and the
              orchard is picked over every 4-6 days until rain sets in, when the exudation of gum
              ceases. Gum is also spontaneously exuded from wild trees, but this is usually rather
              darker in color and not so valuable.

              Description
                     Gum Arabic occurs in rounded or ovoid tears, of variable size, usually about
              0.5-2  cm  in  diameter; whitish or  yellowish white; opaque from  the  presence of
              numerous small fissures in the outer part of the tears; in consequence of these, they
              easily break up into a number of small transparent angular fragments with glistening
              vitreous surface; almost odourless; taste, bland and mucilaginous.
                     Powdered  Gum  Arabic  is  white  to  yellowish  white,  showing  under  the
              microscope angular particles, traces of or no starch granules, occasional particles of
              vegetable tissues, and no mucilaginous cell walls.

              Solubility
                     1 g of Gum Arabic is almost completely soluble in 1 ml of water. It is insoluble
              in alcohol 90 %

              Tests for Identity
              1-  An aqueous solution of gum Arabic (1/1) is translucent, viscous, slightly acidic
                 to litmus paper and not glairy, and when diluted with water and allowed to stand,
                 no gummy deposit separates.
              2-  Optical  activity:  An  aqueous  solution  of  gum  Arabic  (1/10)  is  slightly
                 laevorotatory.
              3-  Test for oxidase enzyme: To an aqueous solution of gum Arabic (1/5), add few
                 drops of solution of H 2O 2 and few drops of benzidine T.S., shake, and allow to
                 stand;  a  deep  blue  or  a  greenish-blue  colour  is  slowly  formed  (c.f.  Gum
                 Tragacanth).








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