Page 339 - Pharmacognosy 2 PG303
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Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D


              Uses
                     Ammoniacum is used as stimulant, carminative, antiseptic and expectorant.


                                                       Olibanum

              Syn.:  Frankincense

                     Olibanum is the oleo-gum-resin obtained from Boswellia carterii and possibly
              other species of Boswellia (Fam. Burseraceae). The plant is a small tree growing in
              southern Arabia and in Somali land near the coast.

              Preparation
                     Like the trees that yield myrrh, they contain schizo-genous ducts in the bark,
              in which an oleo-gum-resin is secreted.  The Somalis incise the bark and collect the
              oleo-gum-resin as soon as it has sufficiently dried.  The drug is conveyed to Aden,
              stored and exported to Europe.

              Description
                     Olibanum occurs in small tears varying from 0.5-3 cm in length and usually
              ovoid, pear-shaped or club-shaped, but sometimes stalactic in form, occasionally
              agglutinated  into  small  masses.    They  are  usually  of  a  pale  yellowish  color,
              frequently with a greenish, bluish, or reddish tinge, semi-translucent and covered
              with a dull white dust.  The surface of the tear being dull even after the dust has been
              removed.    They  are  brittle,  and  internally  are  opalescent  and  translucent,  the
              fractured surface being dull and waxy.  The drug has a fragrant balsamic odor and
              an  aromatic  slightly  bitter  taste  and  softens  to  a  plastic  mass  when  chewed.    It
              produces a whitish emulsion upon trituration with water.

              Constituents
                     Olibanum consists mainly of resin (60-70 %), gum (27-35 %) and volatile oil
              (5-7 %).  These constituents were further classified according to their solubility in
              alcohol into: components soluble in alcohol 72 % including free boswellic acid (33
              %), combined boswellic acid (1.5 %), olibanoresene (33 %), volatile oil (7.0 %) and
              bitter principal (05 %), and components insoluble in alcohol 28 % including gum
              of the acacia type (20 %), bassorin (6.0 %) and vegetable debris 2.0 %).

                     The volatile oil is yellowish and fragrant, it contains pinene, dipentene and
              phellandrene, but the aromatic constituent is not yet known.

              Uses






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