Page 66 - Pharmacognosy 2 PG303
P. 66

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

                     Powder
                     Powdered Ammi visnaga is brown in color and possesses a faint aromatic
              odor  and  an  aromatic  bitter  slightly  pungent  taste.  It  is  characterized
              microscopically by the following fragments:
                     1.  Fragments of pericarp with a few brownish pieces of vittae, reticulate
                         cells, vessels, and fibers.
                     2.  Fragments showing the porous cells of the innermost layer of mesocarp
              crossed  by  and  intimately  united  with  endocarpal  cells  showing  parquetry
              arrangement.
                     3.  Fragments showing brownish cells of seedcoat separately or adhering to
              the endocarp cells.
                     4. Numerous fragments of the endosperm formed of polygonal thick-walled
              cellulosic  cells  containing  oil  droplets  and  aleurone  grains  with  micro-rosette
              crystals of calcium oxalate.
                     5. Fragments of epicarp formed of polygonal cells with striated cuticle and
              occasional crystals of calcium oxalate.
                     6. No hairs and starch granules are present.





































                     Constituents
                     1.  Bitter  principles  Khellin  (0.5-1%)  visnagin  (0.1  %)  Khellol  glucoside
              (0.3%).
                     2. Coumarin derivatives: Samidin dihydrosamidin and visnadin.
                     3. Flavone glycosides (mono and disaccharides of quercetin and kaempferol.
                     4. Fixed oils and proteins.




                                                            37
   61   62   63   64   65   66   67   68   69   70   71