Page 258 - Pharmacognosy 2 PG303 (1)
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Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D










































                     Powdered Rhatany root; 1, cork in surface view; 2, wood fibers with prisms
                     in  the  cells;  3,4,  starch  granules  isolated  and  in  cells;  5,  wood
                     parenchyma; 6,7, wood elements; 8, isolated prisms

              Tests for Identity
                     1-  On  micro-sublimation,  powdered  Rhatany  root  gives  colorless  droplets
              which solidify after some time, giving alcohol non-polarizing aggregates; and with
              FeC1 3 T. S., a faint red color.

                     2- Macerate about 0.5 gm of powdered Kramaria with 5cc alcohol for 12 hours,
              with occasional shaking and filter. To the filtrate, add alc. lead acetate T. S., drop by
              drop, till no more precipitate is formed and filter, both residue and filtrate possess a
              red color (distinction from other Rhatany roots).
                     3-  On  diluting  the  tincture  of  Kramaria  with  water,  it  becomes  cloudy
              (distinction from Para Rhatany).

              Constituents
                     Up to 15% condensed (catechol) tannins, which are localized in the bark. On
              prolonged storage the content decreases, owing to increasing condensation of the
              tannins  (conversion  to  insoluble  phlobaphenes,  so-called  krameria  red).  Other
              constituents: lipophilic  benzofuran derivatives, starch, sugar, N-methyl-tyrosine,.
              etc.




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