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Quellen, Referenzen und Studien:




     Eine kleine Zusammenstellung der Studien, die zur Entwicklung von Balance Plus herangezogen wurden,
     sowie aktuelle Studien, die die äußere Anwendung von CBD bei bestimmten Beschwerden des Bewegung-
     sapparates unterstützen.

     Auf Anfrage können die Informationen und Links zu anderen Studien zur Verfügung gestellt werden.

     1. Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis
     (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851925/  Hammell DC, Zet al. J Pain. 2016)
     2. Essential Oils as Skin Permeation Boosters and Their Predicted Effect Mechanisms
     (https://www.dermatoljournal.com/articles/essential-oils-as-skin-permeation-boosters-and-their-predicted-effect-mechanisms.html#:~:text=Essential Ufuk Koca
     Caliskan*, Methiye Mancak Karakus 2020)
     3. Industry perceptions of cannabidiol use in horses
     (https://www.sciencedirect.com/science/article/abs/pii/S073708062300309X N. Heidorn, D. Cassels, M. Cater, Journal of Equine Veterinary Science 2023)
     4. Evaluation of oral supplementation of cannabidiol (CBD) in horses; Journal of Equine Veterinary Science
     (https://www.sciencedirect.com/science/article/pii/S0737080621001556 L. Cohen, et al. 2021)
     Cellular distribution of cannabinoid-related receptors TRPV1, PPAR-gamma, GPR55 and GPR3 in the equine cervical dorsal root ganglia
     (https://pubmed.ncbi.nlm.nih.gov/34418142/  G. Galiazzo et al. Equine Vet Journal 2021)
     The cannabinoid receptors system in horses: Tissue distribution and cellular identification in skin
     (https://pubmed.ncbi.nlm.nih.gov/35801813/ Piotr Kupczyk 2022)
     Mode of action of cannabinoids on nociceptive nerve endings
     (https://pubmed.ncbi.nlm.nih.gov/19306092/ Michaela Kress, R Kuner, Epub 2009)
     Transdermal drug permeation of micromolecules containing CBD
     (https://www.researchgate.net/publication/320417640_Transdermal_drug_permeation_of_micromolecules_containing_CBD  J. Resnick, Controlled Release Society 2017)
     Transdermal delivery of drugs with differing lipophilicities using azone analogs as dermal penetration enhancers
     (https://pubmed.ncbi.nlm.nih.gov/8748324/  C A Phillips , B B Michniak 1995)
     Endocannabinoid System Components: Overview and Tissue Distribution
     (https://pubmed.ncbi.nlm.nih.gov/31332731/ Neal Joshi, Emmanuel S Onaivi 2019)
     Current Status and Prospects for Cannabidiol Preparations as New Therapeutic Agents
     (https://pubmed.ncbi.nlm.nih.gov/27285147/ Fasinu PS, et al. 2016)
     Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis
     (https://pubmed.ncbi.nlm.nih.gov/18416822/ Richardson D 2008)
     Treatment using cannabidiol in a horse with mechanical allodynia
     (https://beva.onlinelibrary.wiley.com/doi/abs/10.1111/eve.13168 K. L. Ellis, E. K. Contino 2019)
     Safety and behavioural effects of cannabidiol applied as an oral administration in horses
     (https://www.sciencedirect.com/science/article/abs/pii/S0737080621002288 E. Hill, W. Byrne 2021)

     Novel Analgesics and the Impact of Route of Administration in the Horse
     (https://etd.auburn.edu/handle/10415/7015 Davis, Heather 2019)

     Enhanced Skin Penetration of Cannabidiol Using Organosilane Particles as Transdermal Delivery Vehicles
     (https://pubmed.ncbi.nlm.nih.gov/36986659/  Zahra Khabir et al. 2023)
     Cannabinoids in pain management: CB1, CB2 and non-classic receptor ligands
     (https://pubmed.ncbi.nlm.nih.gov/24836296/  Mellar P Davis 2014)
     Cannabinoid receptors are expressed in equine synovium and upregulated with synovitis
     (https://pubmed.ncbi.nlm.nih.gov/35836386/ Ludovic Miagkoff 2023)
     Equine Research on the Short-Term Effects of Cannabidiol for the Treatment of Chronic Pain and/or Anxiety
     (https://www.panacealife.com/wp-content/uploads/2020/02/Final-Equine-Study.pdf 2020)

     Evaluation of CBD Supplementation in the Horse
     (https://digitalcommons.murraystate.edu/cgi/viewcontent.cgi?article=3402&context=postersatthecapitol K. Jones et al. 2023-Project still in progress)
     Cannabinoids in veterinary medicine: Is there evidence to support the trend?
     (https://beva.onlinelibrary.wiley.com/doi/10.1111/eve.13199 M. A. Mercer, J. L. Davis 2019)


      Fa. Adrienne Tomkinson
      ImPuls Methode
      T +43�676�847 131 857
      E adrienne@impulsmethode.at
      W impulsmethode.at
      UID: ATU70222369
      Gerichtsstand Innsbruck
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