Page 34 - Medical Parasitology_ A Textbook ( PDFDrive )

26 5 Hemoflagellates

Fig. 5.1 Trypanosoma brucei gambiense trypomastigotes

Tsetse fly Stages Human Stages
Epimastigotes multiply Tsetse fly takes
in salivary gland They 1 a blood meal
transform into metacyclic (injects metacyclic trypomastigotes) Injected metacyclic
trypomastigotes. trypomastigotes transform
2 into bloodstream
8 trypomastigotes, which
are carried to other sites.
i

7 3
Procyclic trypomastigotes Trypomastigotes multiply by
leave the midgut and transform binary fission in various
into epimastigotes. body fluids, e.g., blood,
lymph, and spinal fluid.
Tsetse fly takes
5 a blood meal
(bloodstream trypomastigotes
are ingested)
6 d
Bloodstream trypomastigotes
transform into procyclic 4 Trypomastigotes in blood
trypomastigotes in tsetse fly’s
midgut. Procyclic trypomastigotes
multiply by binary fission
i = Infective stage
d = Diagnostic stage
Fig. 5.2 Life cycle of Trypanosoma brucei gambiense (Reproduced from https://www.cdc.gov/
dpdx/trypanosomiasisafrican/index.html)