Page 333 - Pharmacognosy 2 PG303

Pharmacognosy-2 (PG303) Level 2 Clinical Pharmacy-Pharm D

Uses
Copaiba was used as a genitourinary disinfectant. It has diuretic, stimulant,

expectorant and laxative properties.

Male Fern Oleo-resin

Syn.: Oleo-resina Filicis; Oleoresina Aspidii; Extractum Filicis Liquidum;
Extractum Filicis Ethereum; Extract of Male Fern; Aspidium Oleo-resin.

Preparation
Male Fern oleo-resin may be prepared by exhausting male fern in moderately

coarse powder, by percolation with ether. Remove the ether, and evaporate the
remainder of the percolate on a water-bath until an oleo-resinous extract remains.
Determine the proportion of filicin in the extract by the method of assay. We add,
if necessary a sufficient quantity of a suitable official fixed oil to produce Oleo-
resina Filicis” of the required strength. Male Fern Oleo-resin contains not less than
24 % and not more than. 26 % w/w of crude filicin.

Description
Male Fern Oleo-resin is a thick, dark green liquid, frequently depositing a

granular, crystalline substance; odor, agreeable; taste bitter and astringent.

Solubility
Male Fern Oleo-resin is insoluble in water. It is soluble in ether, and not less

than 85 % of it is soluble in petroleum ether.

Constituents
Flicin, filmarone, filicic acid, fixed oil, tannic acid and resins,

Test for Identity
Mix about 0.1 g of Male Fern Oleo-resin and 0.2 g of talc, shake vigorously

with 10 ml of hot alcohol, and then filter. Add to 1 ml of the filtrate 9 ml of alcohol;
a light green solution, which turns brownish, on the addition of 1 drop of ferric
chloride T.S. is obtained.

Uses
Aspidium oleo-resin is an anthelmintic, specifically a taeniafuge.

OLEO-GUM-RESINS
Resins may also occur in association with gums and volatile oil, e.g. Myrrh,
Asafoetida, Galbanum, Ammoniacum, Olibanum and Mastic.

275