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Initial symptoms of PPH may be very minor, and diagnosis may be

                  delayed for several years until symptoms worsen. Typical symptoms may
                  include shortness of breath following exertion, excessive fatigue,

                  dizziness, fainting, weakness, ankle swelling, bluish lips and skin, as well
                  as chest pain. It is difficult to detect PPH in medical examination.




                   No one knows what causes PPH; however, research into the cause
                  suggests a number of factors that may be responsible for the disease.
                  Possible causes include genetic or familial predisposition, immune system

                  disease, or drugs or other chemical exposures.

                   Primary pulmonary hypertension is treated with a number of drugs. None
                  of the drugs that can cure or halt the progression of this disease has been

                  found yet, but they may relieve symptoms. Some patients take
                  vasodilators, which help to dilate the blood vessels in the lungs, reducing

                  the blood pressure in them. In addition, anticoagulants may be used to
                  decrease the tendency of the blood to clot in the lungs. Doctors can

                  choose from a variety of drugs that help lower blood pressure in the lungs
                  and improve heart performance in many patients and medication that may

                  take a long period of time. Patients with PPH respond differently to the
                  different medications that relax blood vessels and that no one drug is

                  consistently effective in all patients.


                  Most doctors and patients agree that it is very important for both patients

                  and families to be as informed as possible. This lets everyone understand
                  the illness and apply the information to what is happening. In addition to

                  family and close friends, support groups can help PPH patients and give
                  some valuable experience sharing among sufferers.

                  16. Based on the information in the text, primary pulmonary
                  hypertension….

                   A. is a rare disease that cannot be cured
                   B. implies malfunctioning of cardiovascular

                   C. will contribute to death if left untreated
                  D. optimally needs medical treatments

                   E. requires long-term alternative therapies






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