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(a) Map showing the location of the study area of Delhi, India. (b) Map showing the outline of the study area and the location of eight air quality and weather monitoring stations in Delhi, India.
pre-lockdown (14 March 2020 to 24 March 2020) (r = 0.79), lockdown (25 March 2020 to 31 May 2020) (r = 0.87), and unlock (1 June 2020 to 3 May 2021) (r = −0.75), explaining the variability of about 20-30 per cent in the lockdown period and 18-19 per cent in the unlock period. NO2 explained the maximum variability of 10 per cent and 7 per cent in the total confirmed cases and deaths among the air pollutants, respectively. A generalised linear model could explain 80 per cent and 71 per cent of the variability in confirmed cases and deaths during the lockdown and 82 per cent and 81 per cent variability in the unlock phase, respectively. These findings suggest that these factors may contribute to the transmission of COVID-19 and its associated deaths. The study results would enhance the ongoing research related to the influence of environmental factors. They would be helpful for policymakers in managing the outbreak of COVID-19 in Delhi, India.
Contact info:
sherry@iipsindia.ac.in; doyel11111996@gmail.com
Website link:
https://www.mdpi.com/2076-0817/10/8/1003/htm
COVID-19 pandemic: Insights into molecular mechanisms leading
to sex-based differences in patient outcomes
Recent epidemiological studies analysing sex-disaggregated patient data of coronavirus disease 2019 (COVID-19) across the world revealed a distinct sex bias in the disease morbidity as well as the mortality – both being higher for the men. Similar antecedents have been known for the previous viral infections, including from coronaviruses, such as severe acute respiratory syndrome (SARS) and middle-east respiratory syndrome (MERS). A sound understanding of molecular mechanisms leading to the biological sex bias in the survival outcomes of the patients in relation to COVID-19 will act as an essential requisite for developing a sex-differentiated approach for therapeutic management of this disease. Recent studies that have explored molecular mechanism(s) behind sex-based differences in COVID-19 pathogenesis are scarce.
VOL. IV ISSUE 10
VIGYAN PRASAR 24
COVID-19 SCIENCE & TECHNOLOGY EFFORTS IN INDIA