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AROUND THE REGION
                                                      TM


        Back Cover Story: Prescription for Exercise


        Continued from page 56               endothelial cells, and lung, a possible   cannabinoid levels and changes in mood   could be involved in both the psycholog-
        moderate intensity dramatically in -  role for the endocannabinoid system in   before and after sessions with varying   ical and biological response to exercise.”
        creased concentrations of anandamide in   mediating certain physiological respons-  levels of intensity. The study found that   Through discovering the links between
        blood plasma.                        es to exercise may exist.            subjects experienced a significant boost   exercise and the endocannabinoid sys-
          The runner’s high has been described   Gregory Gerdeman and other col-  in endocannabinoids and improvements   tem, one goal is to develop new treat-
        subjectively as happiness, elation, a feel-  leagues investigated how exercise influ-  in mood following prescribed moderate-  ments for mental health conditions that
        ing of unity with one’s self and/or nature,   ences the endocannabinoid levels of two   intensity exercise.   include exercise. Exercise is an easily
        peacefulness, inner harmony, boundless   mammalian natural athletes - humans   Data from 17 women who suffer with   accessible, free option to feel well, stay
        energy, and a reduction in pain sensation.   and dogs - and a low activity species - fer-  depression was analyzed during the   healthy, improve brain health, strengthen
        An exercise induced altered state of con-  rets. The team published their discovery   study, where each woman completed   bones and muscles, and help optimize
        sciousness has long been appreciated by   that animals that evolved for endurance   two, thirty-minute exercises on station-  one’s endocannabinoid system. It is a
        endurance athletes. This sounds similar   exercise benefit from endocannabinoids   ary bikes at both moderate and preferred   time you can connect with yourself or
        to the way we discuss how one feels   while animals that did not don't experi-  intensity. The data showed that both ses-  others, feel powerful, free, and be out in
        while on psychedelic medicine. There is   ence the pleasures, leading them to pro-  sions on the bike improved mood, but   nature. Perhaps if I prescribed exercise
        actually cross talk that exists between   pose that natural selection used the   only showed an increase in endocannabi-  more to my patients on my prescription
        our Cannabinoid receptor in the brain   endocannabinoid system to motivate   noid levels for moderate intensity exer-  pad, they might be more likely to respect
        (CB1) and our classic serotonin psyche-  endurance exercise in humans. The team   cise. There was no difference for pre-  the treatment plan or perhaps we should
        delic receptor 5HT2A. Therefore, using   publishes their discovery in The Journal   ferred intensity.         get our patients familiar with therapies
        cannabis can actually cause a similar   of Experimental Biology.           The study also shows there is some   that do not need to be picked up at a
        altered level of consciousness or psyche-  'Inactive people may not be fit enough   correlation between prescribed exercise   pharmacy…
        delic feeling because of the dimerization   to hit the exercise intensity that leads to   and increase in mood, as opposed to pre-
        between receptors.                   this sort of rewarding sensation.'   ferred exercise. The same team complet-  Dr. Michelle Weiner, Spine and Wellness
          Because activation of the endocannabi-  However, inactive individuals can be   ed a similar study in 2016 that looked at   Centers of America, can be reached at
        noid system reduces pain sensations, and   helped to build up their exercise toler-  the effect of exercise on brain-derived      (305) 974-5533 or
        alters emotional and cognitive processes,   ance until they cross the threshold where   neurotrophic factor or BDNF, a protein   mweiner@spinewellnessamerica.com.
        this finding has implication for some of   they become motivated to exercise by   that regulates neuron growth and sur-
        the psychological effects that accompany   endocannabinoids.              vival. People with depression typically
                                                                                                                        Raichlen, D. A., Foster, A. D., Gerdeman, G. L.,
        exercise. As a result of the presence of   Another study performed by re -  have lower levels of BDNF. The 2016   Seillier, A. and Giuffrida, A. (2012). Wired to run:
        cannabinoid receptors in muscle, skin,   searchers in Wisconsin measured endo-  study found that when women with   exercise-induced endocannabinoid signaling in
                                                                                  depression were prescribed an exercise   humans and cursorial mammals with implications
                                                                                  session similar in intensity to exercise   for the 'runner's high'. J. Exp. Biol. 215, 1331-1336.
                                                                                                                      jeb.biologists.org/content/215/8/1331.abstrac
                                                                                  they selected, their BDNF levels were sig-
                                                                                  nificantly higher following the pre-  Serum Endocannabinoid and Mood Changes
                                                                                                                      after Exercise in Maj... : Medicine & Science in
                                                                                  scribed session. Therefore, “Having
                                                                                                                      Sports & Exercise (lww.com)
                                                                                  someone else prescribe the exercise


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         54                       May 2021                                                                     cannabisnewsflorida.com                                                                                     Cannabis News Florida
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