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         Back Cover Story:  Chronic Pain,

         Opioids, and Cannabis


         Continued from page 44              the reuptake of ENT1, the concentration
        cannabis as a medicine, namely, that it   of adenosine in the brain can increase.
        may serve as an alternative to or as an   In addition to pain relief, CBD offers
        adjunct treatment to opioids.        several other therapeutic qualities. For
          Investigation of the medicinal proper-  instance, CBD has shown the potential to
        ties of cannabis shows promise as a nat-  relieve symptoms of anxiety and depres-
        ural approach to pain relief. One illustra-  sion, stimulate bone growth, inhibit can-
        tion is the phytocannabinoid, cannabidi-  cer cell proliferation, and even slow the
        ol, or CBD. This naturally occurring   progression of neurodegenerative disease
        compound found in cannabis plants has   states such as Alzheimer’s. Despite the
        demonstrated the ability to modulate   growing number of medicinal benefits of
        numerous receptors throughout the    CBD, a need for a more detailed exami-
        body in a non-intoxicating manner. In   nation of its medicinal benefits still
        2018, investigators demonstrated that   exists. However, until marijuana is
        CBD could act as a natural analgesic in   rescheduled by the DEA, advancing clin-
        mice models. The same group of       ical research and knowledge of cannabis
        researchers concluded that CBD limited   will continue to wait. Regardless, the
        the release of the excitatory neurotrans-  results of the investigations referenced
        mitter, glutamate. Glutamate contributes   previously are promising additions for
        to the over-activation of pain sensation   patients and health care providers look-
        and transmission inside the nervous sys-  ing to supplement or modify convention-
        tem. Similar research completed in 2019,   al pharmaceutical treatments for chronic
        suggested that CBD may even reduce   pain.
        inflammation by limiting the reuptake of
        the inhibitory neurotransmitter, adeno-     For more information, contact Brit
        sine. Researchers propose that CBD can   Francis, MS, CC, The Canna Academy,
        repress the protein, equilibrate nucleo-              at (561) 808-6656 or
        side transporter 1 (ENT1). By slowing          thecannaacademy@gmail.com.
























































        Cannabis News Florida                                                                          cannabisnewsflorida.com                                                         September 2020                          41
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