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easily quantified, and of a discrete and stable amount,   Philosophical and Policy
                     whereas health risks are hard-to-measure probabilities,
                     often involving a small percentage of people likely to suf-  Approaches
                     fer greatly and a large majority likely to experience little
                     effect. When a government agency bans a pesticide, it may   Because we cannot know a substance’s toxicity until we meas-
                     mean considerable economic loss for the manufacturer and   ure and test it, and because there are so many untested chemi-
                     potential economic loss for the farmer, whereas the benefits   cals and combinations, science will never eliminate the many
                     accrue less predictably over the long term to some percent-  uncertainties that accompany risk assessment. In such a world
                     age of factory workers, farmers, and the general public.   of uncertainty, there are two basic philosophical approaches
                     Because of the lack of equivalence in the way costs and   to categorizing substances as safe or dangerous (Figure 14.19).
                     benefits are measured, risk management frequently tends to
                     stir up debate.
                        In the case of bisphenol A, eliminating plastic linings   Two approaches exist for
                     in our food and drink cans could do more harm than good,   determining safety
                     because the linings help prevent metal corrosion and the con-
                     tamination of food by pathogens. Alternative substances exist   One approach is to assume that substances are harmless until
                     for most of BPA’s uses, but replacing BPA with alternatives   shown to be harmful. We might nickname this the “innocent-
                     will  entail  economic  costs  to  industry,  and  these  costs  are   until-proven-guilty” approach. Because thoroughly testing
                     passed on to consumers in the prices of products. Such com-  every existing substance (and combination of substances) for
                     plex considerations can make risk management decisions dif-  its effects is a hopelessly long, complicated, and expensive
                     ficult even if the science of risk assessment is fairly clear. This   pursuit, the innocent-until-proven-guilty approach has the
                     difficulty may help account for the hesitancy of U.S. regula-  virtue of facilitating technological innovation and economic
                     tory agencies to issue restrictions on BPA so far. As of 2013,   activity. However, it has the disadvantage of putting into wide
                     both the FDA and the EPA were continuing to review options   use some substances that may later turn out to be dangerous,
                     for managing risk from BPA.                          such as happened with the pesticide DDT.




                                            “Innocent until proven         Precautionary
                     Sequence of events       guilty” approach           principle approach


                      Industrial research and
                         development




                      Pre-market testing by
                      industry, government,
                         and academic
                           scientists       Limited testing; most   Rigorous testing; only the safest
                                          products brought to market  products brought to market

                                                                                                Figure 14.19 Two main
                        Consumer use of                                                         approaches can be taken to
                           products                                                             introduce new substances to
                                            Some products harm           Minimal impact on      the market. In one approach,
                                               human health                human health
                                                                                                substances are “innocent until
                                                                                                proven guilty”; they are brought to
                      Post-market testing by                                                    market relatively quickly after limited
                      industry, government,                                                     testing. Products reach consum-
                      and academic scientists                                                   ers more quickly, but some fraction
                                          Rigorous testing demanded    Limited testing required
                                                                                                of them (blue bottle in diagram)
                                                                                                may cause harm to some fraction
                                                                                                of people. The other approach is to
                      Regulations and bans                                                      adopt the precautionary principle,
                       of unsafe products                                                       bringing substances to market cau-
                                                                                                tiously, only after extensive testing.
                                            Unsafe products recalled
                                                                                                Products that reach the market
                                                                                                should be safe, but many perfectly
                      Consumer use of safe                                                      safe products (purple bottle in
                           products                                                             diagram) will be delayed in reaching
             400                                                                                consumers.







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