Page 165 - CSIR-IGIB Annual Report 2020-21

INSPIRE FELLOW | Neuroepigenetics

Arpita Konar is interested in understanding the mechanism by which early life traumatic experiences
impact brain functions and behaviour posing risk for mental illness. Using animal models of peripubertal
stress she is exploring the epigenetic changes in brain that might trigger abnormal psychiatric and
cognitive manifestations in adulthood.

Publications

Role of nutraceuticals in cognition during aging and related disorders. Singh P, Sivanandam TM, Konar A*, Thakur
MK, Neurochem Int, 2021, 143:104928.

Identification of caffeic acid phenethyl ester (CAPE) as a potent neurodifferentiating natural compound that

improves cognitive and physiological functions in animal models of neurodegenerative diseases. Konar A, Kalra RS,
Chaudhary A, Nayak A, Guruprasad KP, Satyamoorthy K, Ishida Y, Terao K, Kaul SC, Wadhwa R, Front Aging Neurosci,
2020,12:561925.

Bacosides encapsulated in lactoferrin conjugated PEG-PLA-PCL-OH based polymersomes act as epigenetic
modulator in chemically induced amnesia. Neurochem Res. Goyal K, Konar A, Kumar A, Koul V, 2020, 45:796-808.

Preprints
Early life trauma leads to violent behavior and its inheritance by impairing local thyroid hormone availability in
brain. Rawat RS, Bhambri A, Pal M, Roy A, Jain S, Pillai B, Konar A* bioRxiv, 2021,

doi:https://doi.org/10.1101/2021.07.05.448713

Annual Report 2020-21 162