Page 26 - Labatt Brain Tumour Research Centre Annual Report 2023 to 2024

Publications
2023
Chen X, Momin A, Wanggou S, Wang X, Min HK, Dou
W, Gong Z, Chan J, Dong W, Fan JJ, Xiong Y, Talipova K,
Zhao H, Chen YX, Veerasammy K, Fekete A, Kumar SA,
Liu H, Yang Q, Son JE, Dou Z, Hu M, Pardis P, Juraschka
K, Donovan L, Zhang J, Ramaswamy V, Selvadurai H,
Dirks PB, Taylor MD, Wang LY, Hui CC, Abzalimov R, He Y,
Sun Y, Li X, Huang X. Mechanosensitive brain tumor cells
construct blood-tumor barrier to mask chemosensitivity.
Neuron 2023. 111:30-48.
Das A, Tabori U, Sambira Nahum LC, Collins NB, Deyell
R, Dvir R, Faure-Conter C, Hassall TE, Minturn JE,
Edwards M, Brookes E, Bianchi V, Levine A, Stone SC,
Sudhaman S, Sanchez-Ramirez S, Ercan AB, Stengs L,
Chung J, Negm L, Getz G, Maruvka YE, Ertl-Wagner B,
Ohashi PS, Pugh T, Hawkins C, Bouffet E, Morgenstern
DA. Efficacy of nivolumab in pediatric cancers with
high mutation burden and mismatch-repair deficiency.
Clin Cancer Res. 2023 May 1:CCR-23-0411
Dave BM, Chen X, McCready F, Charton C, Morley
RM, Tailor JK, Ellis J, Huang X, Dirks PB. Directed
differentiation of human hindbrain neuroepithelial stem
cells recapitulates cerebellar granule neurogenesis.
Development. 2023 Jul 1;150(13):dev201534.
Dong W, Fekete A, Chen X, Liu H, Beilhartz GL, Chen X,
Bahrampour S, Xiong Y, Yang Q, Zhao H, Kong T, Morioka
MS, Jung G, Kim JE, Schramek D, Dirks PB, Song Y, Kim
TH, He Y, Wanggou S, Li X, Melnyk RA, Wang LY, Huang
X. A designer peptide against the EAG2-Kvβ2 potassium
channel targets the interaction of cancer cells and
neurons to treat glioblastoma. Nat Cancer. 2023
Oct;4(10):1418-1436.
26
IMAGINE 2023-24
Li A, Gaebe K, Zulfiqar A, Lee G, Jerzak KJ, Sahgal A,
Habbous S, Erickson AW, Das S. Association of brain
metastases with survival in patients with limited or
stable extracranial disease: A systematic review and
meta-analysis. JAMA Netw Open. 2023; 6(2): e230475.
Lubanszky E, Hawkins C. Modeling the landscape of
histone-mutant pediatric high-grade gliomas: A study
in partner alterations. Cancer Discov. 2023 Jul
7;13(7):1516-1517.
Patel Z, Cho M, Das S. The role of immune checkpoint
inhibitors in patients with intracranial metastatic
disease. J Neurooncol. 2023 Feb; 161(3):469-478.
2024
Bajin IY, Levine A, Dewan MC, Bennett J, Tabori
U, Hawkins C, Bouffet E. Understanding diffuse
leptomeningeal glioneuronal tumors. Childs Nerv Syst.
2024 Aug;40(8):2359-2366.
Das A, Ercan AB, Tabori U. An update on central nervous
system tumors in germline replication-repair deficiency
syndromes. Neurooncol Adv. 2024 Jun 19;6.
Das A, Fernandez NR, Levine A, Bianchi V, Stengs LK,
Chung J, Negm L, Dimayacyac JR, Chang Y, Nobre L,
Ercan AB, Sanchez-Ramirez S, Sudhaman S, Edwards M,
Larouche V, Samuel D, Van Damme A, Gass D, Ziegler
DS, Bielack SS, Koschmann C, Zelcer S, Yalon-Oren M,
Campino GA, Sarosiek T, Nichols KE, Loret De Mola R,
Bielamowicz K, Sabel M, Frojd CA, Wood MD, Glover JM,
Lee YY, Vanan M, Adamski JK, Perreault S, Chamdine O,
Hjort MA, Zapotocky M, Carceller F, Wright E, Fedorakova
I, Lossos A, Tanaka R, Osborn M, Blumenthal DT,
Aronson M, Bartels U, Huang A, Ramaswamy V, Malkin
D, Shlien A, Villani A, Dirks PB, Pugh TJ, Getz G, Maruvka
YE, Tsang DS, Ertl-Wagner B, Hawkins C, Bouffet E,
Morgenstern DA, Tabori U. Combined Immunotherapy
Improves Outcome for Replication-Repair-Deficient
(RRD) High-grade glioma failing anti-PD-1 monotherapy:
A report from the International RRD Consortium. Cancer
Discov. 2024 Feb 8;14(2):258-273.
Das A, MacFarland SP, Meade J, Hansford JR, Schneider
KW, Kuiper RP, Jongmans MCJ, Lesmana H, Schultz
KAP, Nichols KE, Durno C, Zelley K, Porter CC, States LJ,
Ben-Shachar S, Savage SA, Kalish JM, Walsh MF, Scott
HS, Plon SE, Tabori U. Clinical updates and surveillance
recommendations for DNA replication repair deficiency
syndromes in children and young adults. Clin Cancer
Res. 2024 Aug 15;30(16):3378-3387.
Ercan AB, Aronson M, Fernandez NR, Chang Y, Levine A,
Liu ZA, Negm L, Edwards M, Bianchi V, Stengs L, Chung
J, Al-Battashi A, Reschke A, Lion A, Ahmad A, Lassaletta
A, Reddy AT, Al-Darraji AF, Shah AC, Van Damme A,
Bendel A, Rashid A, Margol AS, Kelly BL, Pencheva
B, Heald B, Lemieux-Anglin B, Crooks B, Koschmann
C, Gilpin C, Porter CC, Gass D, Samuel D, Ziegler DS,
Blumenthal DT, Kuo DJ, Hamideh D, Basel D, Khuong-
Quang DA, Stearns D, Opocher E, Carceller F, Baris
Feldman H, Toledano H, Winer I, Scheers I, Fedorakova
I, Su JM, Vengoechea J, Sterba J, Knipstein J, Hansford
JR, Gonzales-Santos JR, Bhatia K, Bielamowicz KJ,
Minhas K, Nichols KE, Cole KA, Penney L, Hjort MA,
Sabel M, Gil-da-Costa MJ, Murray MJ, Miller M, Blundell
ML, Massimino M, Al-Hussaini M, Al-Jadiry MF, Comito
MA, Osborn M, Link MP, Zapotocky M, Ghalibafian M,
Shaheen N, Mushtaq N, Waespe N, Hijiya N, Fuentes-
Bolanos N, Ahmad O, Chamdine O, Roy P, Pichurin PN,
Nyman P, Pearlman R, Auer RC, Sukumaran RK, Kebudi
R, Dvir R, Raphael R, Elhasid R, McGee RB, Chami
R, Noss R, Tanaka R, Raskin S, Sen S, Lindhorst S,
Perreault S, Caspi S, Riaz S, Constantini S, Albert S,
Chaleff S, Bielack S, Chiaravalli S, Cramer SL, Roy
S, Cahn S, Penna S, Hamid SA, Ghafoor T, Imam U,