Page 27 - Labatt Brain Tumour Research Centre Annual Report 2023 to 2024

Larouche V, Magimairajan Issai V, Foulkes WD, Lee YY,
Nathan PC, Maruvka YE, Greer MC, Durno C, Shlien A,
Ertl-Wagner B, Villani A, Malkin D, Hawkins C, Bouffet
E, Das A, Tabori U. Clinical and biological landscape of
constitutional mismatch-repair deficiency syndrome: An
International Replication Repair Deficiency Consortium
cohort study. Lancet Oncol. 2024 Mar 26:S1470-
2045(24)00026-3.
Fujita N, Bondoc A, Simoes S, Ishida J, Taccone MS,
Luck A, Srikanthan D, Siddaway R, Levine A, Sabha N,
Krumholtz S, Kondo A, Arai H, Smith C, McDonald P,
Hawkins C, Dedhar S, Rutka J. Combination treatment
with histone deacetylase and carbonic anhydrase 9
inhibitors shows therapeutic potential in experimental
diffuse intrinsic pontine glioma. Brain Tumor Pathol.
2024 Oct;41(3-4):117-131. Epub 2024 Sep 24.
Hammad R, Nobre L, Ryall S, Arnoldo A, Siddaway
R, Bennett J, Tabori U, Hawkins C. The Clinical utility
of a tiered approach to pediatric glioma molecular
characterization for resource-limited settings. JCO Glob
Oncol. 2024 May;10:e2300269.
Dr. Rutka and Angela Scalisi at the Brain Cancer Canada Gala
Ho B, Arnoldo A, Zhong Y, Lu M, Torchia J, Yao F, Hawkins
C, Huang A. Rapid, economical diagnostic classification
of ATRT molecular subgroup using NanoString nCounter
platform. Neurooncol Adv. 2024 Jan 16;6(1):vdae004.
Levine AB, Nobre L, Das A, Milos S, Bianchi V, Johnson
M, Fernandez NR, Stengs L, Ryall S, Ku M, Rana M, Laxer
B, Sheth J, Sbergio S-G, Fedoráková I, Ramaswamy V,
Bennett J, Siddaway R, Tabori U, Hawkins C. (Jul 2024).
Immuno-oncologic profiling of pediatric brain tumors
reveals major clinical significance of the tumor immune
microenvironment. Nature Communications, 15(1), 5790.
Lin C, Smith C, Rutka J. Current immunotherapeutic
approaches to diffuse intrinsic pontine glioma. Front
Genet. 2024 May 7;15:1349612.
Nör C, Ramaswamy V. Leading medulloblastoma
to a differentiation end. Cancer Cell. 2024 Aug
12;42(8):1331-1333.
Plant-Fox AS, Tabori U. Future perspective of targeted
treatments in pediatric low-grade glioma (pLGG): The
evolution of standard-of-care and challenges of a new
era. Childs Nerv Syst. 2024 Jul 31.
Raghuram N, Temel EI, Kawamata T, Kozma KJ, Loch
AJ, Wang W, Adams JR, Muller WJ, Egan SE. Elevated
expression of wildtype RhoC promotes ErbB2- and
Pik3ca-induced mammary tumor formation. Breast
Cancer Res. 2024, May 28; 26(1):86, 1-12.
Siddaway R, Tabori U, Hawkins C. Immuno-oncologic
profiling of pediatric brain tumors reveals major clinical
significance of the tumor immune microenvironment.
Nat Commun. 2024 Jul 10;15(1):5790.
Members of the Rutka lab at the BTRC Scientific Retreat
Visvanathan A, Saulnier O, Chen C, Haldipur P, Orisme
W, Delaidelli A, Shin S, Millman J, Bryant A, Abeysundara
N, Wu X, Hendrikse LD, Patil V, Bashardanesh Z, Golser
J, Livingston BG, Nakashima T, Funakoshi Y, Ong W,
Rasnitsyn A, Aldinger KA, Richman CM, Van Ommeren
R, Lee JJY, Ly M, Vladoiu MC, Kharas K, Balin P, Erickson
AW, Fong V, Zhang J, Suárez RA, Wang H, Huang N,
Pallota JG, Douglas T, Haapasalo J, Razavi F, Silvestri E,
Sirbu O, Worme S, Kameda-Smith MM, Wu X, Daniels C,
MichaelRaj AK, Badhuri A, Schramek D, Suzuki H, Garzia
L, Ahmed N, Kleinman CL, Stein LD, Dirks P, Dunham
C, Jabado N, Rich JN, Li W, Sorensen PH, Wechsler-
Reya RJ, Weiss WA, Millen KJ, Ellison DW, Dimitrov DS,
Taylor MD. Early rhombic lip Protogenin+ve stem cells
in a human-specific neurovascular niche initiate and
maintain group 3 medulloblastoma. Cell. 2024 Jun
26:S0092-8674(24)00651-2.
ON THE BACK COVER
Group photo from the 2023 BTRC
Scientific Retreat held at Killarney
Mountain Lodge.
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