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1294 Technique of Intraperitoneal Chemotherapy: Normothermic and Hyperthermic

AB C

Figure 1. Titanium port with 14.3F silicone catheter,fenestrated, with cuffs (A) and without cuffs (B) approved by Food and Drug Ad-
ministration: Bard Access Systems, Inc Salt Lake City, UT, USA Reorder number:0603000 and 0603006. C. Plastic port with 9.6F silicone
catheter pre-attached, single lumen, no cuff. Bard Access Systems, Inc Salt Lake City, UT, USA reorder number: 0602660

dialysis (11). Subsequently, a fully implantable port to the port or unattached and Dacron cuff to ensure a
attached to a Tenckhoff-style catheter (12) was developed, secure attachment to the fascia and tissues of the anterior
whilst a device consisting of a Tenckhoff intraperitoneal abdominal wall) (Table 1). Analysis of GOG-172 and
catheter attached to a subcutaneous port that was used other data guided the conclusion that catheters with
for venous access was later given FDA (Food and Drug multiple fenestrations were prone to obstruction and
Administration) approval (Figure 1A, B). that Dacron cuffs lead to infection, as did insertion of
the port at the time of left colon resection. The initial
The characteristics of access devices include the recommendation was to use venous access catheters
subcutaneously-placed port through which the catheter (which had no cuff or fenestrations), and to avoid placing
is accessed (variables: size, composition) and the ports at contaminated surgery and to remove them after
catheter (variables: diameter or F size, composition, treatment was completed (5).
single lumen or multiple fenestrations, pre-attached

Table 1. Examples of Ports Used for IP Delivery of Chemotherapy

Catheter

Company Number Port Attached Size (F)1 Material Fenestrated Auff

Bard 0605300 Titanium no 8 Polyurethane2 no no

Bard 0602660 Plastic4 yes 9.6 Silicone3 no no

Bard (Figure 1B) 0602680 Plastic no 9.6 Silicone no no

Bard 0602870 Titanium no 9.6 Silicone no no

Bard 0602270 Titanium yes 9.6 Silicone no no
Bard5 (Figure 1A) 0603006 Titanium no 14.3 Silicone yes no

Bard5 (Figure 1B) 0603000 Titanium no 14.3 Silicone yes yes
Smith Medical6 21-2000-24 Titanium no yes
14.7 Polyurethane yes

1F=French refers to the diameter of the catheter: 1 Fr = 0.33 mm
2Patented polyurethane that can tolerate taxanes.
3Silicone is softer and more flexible than polyurethane
4Plastic ports are completely compatible with magnetic resonance imaging whereas titanium port manufactured by Bard are compatible to

3 Tesla.
5Federal Drug Administration-approved for intraperitoneal chemotherapy delivery. Bard Access Systems, Inc Salt Lake City, UT, USA
6Port-A-Cath® Peritoneal Implantable Access System. Smith Medical St Paul, MN, USA