Page 42 - Course Guide 2019
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21. Calculate the quantity of Drug Z needed to prepare 100 mL solution, so that when this
3
solution is diluted with water to 1 L will produce a solution with 5 x 10 µg/mL. (Answer:
500 mg)
22. What is the definition of a suspension?
23. Give two examples of diffusible powder.
24. Give one example of suspending agent that is unsuitable for oral products.
25. What is the formula for Compound Tragacanth Powder BP?
26. Is Compound Tragacanth Powder BP suitable for external use? Give your reason.
27. Give one important auxiliary label for suspension.
28. What is the definition of an emulsion?
29. Is there a need to incorporate preservative and antioxidant in an emulsion? State your
reason.
30. Why do you need to use distilled water in the preparation of an emulsion?
31. State the O:W:A ratio for fixed oil, volatile oil and mineral oil.
32. Give two examples of mineral oil.
33. Give two examples of emulgents from different classes (two for each class).
34. You are asked to prepare 200 mL emulsion with Liquid Paraffin BP 36%, Amaranth BP
0.5% and Syrup BP 10%. How much Acacia BP would be needed to prepare this
emulsion? (Answer: 24 g)
35. How much Acacia BP will be needed to prepare 75 mL of an emulsion with 15%
Cinnamin oil? (Answer: 5.6 g)
36. Prepare a full formula to prepare Maize oil 25% v/v emulsion for a 25-year-old patient.
37. Why is hygiene important in preparing a cream?
38. The most suitable way to incorporate a course insoluble powder into a molten ointment
base will be through trituration/fusion/levigation/titration.
REFERENCES
1. Yvonne Tan Tze Fung, Saringat Baie, Peh Kok Khiang, Yusrida Darwis. Pharmacy Practice I (First
English Edition). School of Pharmaceutical Sciences USM 2007.
2. Chris Langley, Dawn Belcher. Pharmaceutical Compounding and Dispensing. Pharmaceutical
Press.
rd
3. A. J. Winfield, R. M. E Richard. Pharmaceutical Practice, 3 ed. Churchill Livingstone 2004.