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Understanding the difference

between stem cells Choosing the right stem cell

for your needs

There are several stem cell types
that are currently being researched, &4$ J14$ )4$ .4$ ".1$
and others that are readily available in &NCSZPOJD TUFN *OEVDFE 1MVSJQPUFOU )BFNBUPQPJFUJD TUFN .FTFODIZNBM TUFN DFMM $PNQBSJTPO "VUPMPHPVT .VMUJMJOFBHF 1PUFOUJBM
the market for treatment. Embryonic DFMM TUFN DFMM DFMM $FMMT
stem cells, and induced pluripotent
stem cells are both pluripotent stem 1MVSJQPUFOU %FNPOTUSBUFE BCJMJUZ UP
cells. However, due to the ethical and 1MVSJQPUFOU 1MVSJQPUFOU #MPPE DFMMT POMZ #POF DBSUJMBHF TLJO 1PUFODZ EJGGFSFOUJBUF JOUP EJGGFSFOU DFMM UZQFT
JODMVEJOH OFVSPOT MJWFS DFMMT IFBSU
safety issues surrounding their use, GBU DFMMT NVTDMF DFMMT BOE CPOF DBOE
they are unable to be used for human DBSUJMBHF GPSNJOH FMMT
treatments in a safe manner, or in any

legal capacity. UP NJMMJPO UP NJMMJPO $FMM $PVOU UP NJMMJPO UP Y
XJUIPVU HFOFUJD FYQBOTJPO PG DFMMT
Haematopoietic stem cells are
cells that form blood cells and are :FT CVU QSJNBSJMZ :FT BMMPHFOFJD TPVSDFT "VUPMPHPVT :FT BVUPMPHPVT POMZ 5IF EPOPS PG UIF
TBNQMF XJMM CF UIF TBNF QFSTPO
typically used in leukaemic patients BMMPHFOFJD BMTP QPTTJCMF SFDFJWJOH UIF TUFN DFMMT GPS USFBUNFOU
after chemotherapy to restore normal
blood cells. They can be extracted from 'SPN DPSE CMPPE 'SPN BEJQPTF UJTTVF &YUSBDUFE GSPN QFSJQIFSBM CMPPE PG UIF
a variety of sources, but typically are ( $4' TUJNVMBUJPO PS FYUSBDUJPO PS IVNBO &YUSBDUJPO QBUJFOU JOUP B TUFSJMF CMPPE CBH
sourced from donors due to blood cell CPOF NBSSPX VNCJMJDBM DPSE UJTTVF 1SPDFTT 5IF CMPPE CBH JT UIFO TFBMFE UP
complications in their own bodies. USBOTQMBOUT QSFWFOU DPOUBNJOBUJPO

Mesenchymal stem cells are µ $PSE CMPPE DVMUVSF µ 6NCJMJDBM DPSE TUFN DFMM
primarily used for sports injuries as SFRVJSFT HFOFUJD FYUSBDUJPO SFRVJSFT
they can regenerate bone and cartilage FYQBOTJPO QSPDFTTFT HFOFUJD FYQBOTJPO
QSPDFTTFT UP CPMTUFS
UP CPMTUFS DFMM DPVOUT
damage while reducing inflammation $BOOPU CF GFBTJCMZ VTFE JO USFBUNFOU CVU XJMM JODVS NVUBUJPO DFMM DPVOUT CVU XJMM JODVS
XJUIPVU DPNQSPNJTJOH TBGFUZ BOE
in joints that cause pain. Though they FUIJDT SJTL NVUBUJPO SJTL
can be extracted from umbilical cord µ ( $4' TUJNVMBUJPO NVTU µ "EJQPTF TUFN DFMM µ $VMUVSFE JO B TQFDJBMJTFE
tissue, these procedures often require CF EPOF TFWFSBM EBZT JOWPMWFT FYUSBDUJPO GSPN NJDSPFOWJSPONFOU PWFS EBZT
a donor; as such, most mesenchymal QSJPS UP JOUFOEFE EBUF UIF GBUUZ UJTTVF UIBU XJUIPVU HFOFUJD NBOJQVMBUJPO
UBLFT VQ UP NJOVUFT
PG FYUSBDUJPO
stem cells are extracted from adipose &YUSBDUFE TBNQMFT NBZ 'SPN UIFSF GVSUIFS $VMUVSF µ $FMMT DPOUBJOFE JO B DMPTFE TZTUFN UP
1SPDFTT
tissue. This extraction is invasive and UIFO VOEFSHP HFOFUJD FYQBOTJPO NBZ NJOJNJTF DPOUBNJOBUJPO
results in low cell counts. FYQBOTJPO UP CPMTUFS CF SFRVJSFE BT µ "MM DVMUVSFE DFMMT TFOU GPS
DFMM DPVOUT CVU XJMM FYUSBDUJPO UZQJDBMMZ DPOUBNJOBUJPO UFTUJOH QSJPS UP VTF JO
In summary, there are pros and JODVS NVUBUJPO SJTL ZJFMET MPX DFMM DPVOUT USFBUNFOUT
cons to different stem cell types. Here µ #POF NBSSPX 5IJT XJMM JODVS B
NVUBUJPO SJTL
you may find a comparison between USBOTQMBOUT JOWPMWF
FYUSBDUJPO GSPN EPOPST
AMPC and existing stem cell types GPMMPXFE CZ TUPSBHF
available: VOUJM UIF DFMMT BSF SFBEZ
UP CF USBOTQMBOUFE

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