Page 124 - The Miracle in the Cell Membrane
P. 124

(1)                                    (2)
                                                            These diagrams show
                                                           the entry into the cell of
                                                           LDL   (low  density
                                                           lipoprotein) particles
                                                           by means of endocyto-
                                                           sis. LDL particles build
                                                           a covalent bond with
                 Clathrin
                 covered        0.2 μm                     the protein ferritin, and
                 cavity   LDL-ferritin      LDL-ferritin   then the cell membrane
                  (3)                                    (4)  forms a sac by which
                                                           these  particles  are
                                                           absorbed. Under an
                                                           electron microscope,
                                                           every small iron parti-
                                                           cle within the ferritin
                                                           can be seen as a small
                                                           dot.



                     from the cell's sur face and in the form of a cap sule, joins
                     the cell cyto plasm. During this proc ess, cal ci um ions
                     need to be present in the extra cel lu lar fluid because cal ci -
                     um allows the pro teins, which per mit the cap sule to sep -
                     a rate from the cell mem brane, to shrink.
                        Pinocytosis can be observed con stant ly in most cell
                     mem branes, although in cer tain cells it may take place
                     very rap id ly. In macro pha ges, for instance, a total of 3%
                     of the cell mem brane may be taken into the cell in the
                     form of sacs in the space of one minute. These sacs used






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