Page 226 - The Miracle in the Cell Membrane
P. 226

The Miracle in the Cell Membrane



                     most delicate balance for one cell to be able to bind to
                     another, and it is impossible for that equilibrium to have
                     attained its ideal form by trial and error.



                        Another of the Cell's Essential Abilities:
                        Crawling

                        If cells could not move, life would be impossible.
                     During crawling, the cell extends fan-like protrusions
                     known as lamellae that permit a temporary attachment to
                     the adjacent surface and slide forward, dragging the cell
                     behind them. This process is made possible by the cell's
                     constantly changing shape. To do so, that the cytoplasm
                     inside the cell wall must have the property of a semi-
                     solid and be adhesive in such a way as to form protru-
                     sions extending to the outside. But at the same time, the
                     inside of the cell must also have solid structural elements
                     to constitute a flexible skeleton.
                        Evidently, the cell's crawling ability depends on the
                     cytoplasm being readily deformable so that the cell's inte-
                     rior can be drawn into an advancing protrusion. If too
                     viscous, the cell's contents would be immobilized. The
                     cell must be able to reversibly adhere to a substratum,
                     and, as you just saw, the property of adhesion depends
                     on the strength of weak chemical bonds. The cell must be
                     able to generate enough traction to pull its mechanically
                     rigid scaffold. If the viscosity of water, the energy levels
                     of weak chemical bonds and the power of the traction
                     forces were all slightly different from what they are, such






                                              224
   221   222   223   224   225   226   227   228   229   230   231