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DURABILITY OF A LOW SHRINKAGE




 TEGDMA/HEMA-FREE RESIN





 COMPOSITE SYSTEM IN CLASS II




 RESTORATIONS.











        marketed during the last years 10–12 .   high hydrophilicity and detergent   HEMA in adhesives may lead to
 DESPITE THE INCREASING USE OF RESIN COMPOSITES,  Biocompatibility of dental materials   activity in liposomes. It can penetrate   phase separation between water
        is an important consideration for    all biologicalcompartments, the      and the adhesive monomers  27–29 . It
 THERE ARE STILL SEVERAL REMAINING PROBLEMS TO BE SOLVED.  the patient and clinician. Many in   extracellular and intracellular space,   has been shown that HEMAinhibited
                                                                                  intracellular tyrosine phosphorylation
                                             including cell nuclei and membranes.
        vitro studies have shown that the
        polymerization reaction, producing   The monomer showed chemical–         20] , induced cell growth inhibition and
        the cross-linked polymer matrix from   biological interactions with many   cycle perturbation   and is a potent
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        the dimethacrylate resinmonomers, is   cell structures or processes like   inducer of apoptotic cell death  .
        never complete. It has been reported   inhibition of cell growth and decrease   Cell mutation has been observed
        that of the methacrylate groups,     of the intracellular glutathione level   after exposure to both TEGDMA
 he objective of this   estimated. Results. Three molar teeth   cross-linking of the polymer chains.  25%–60% may remain unreacted and   18,19,21,22 . The quantity of TEGDMA   and HEMA 32,33  as well as increased
 randomized controlled   showed mild post-operative sensitivity   The free curing contraction for   about 10% of the available groups   leaching from restorative materials   intracellular concentrations of
 Tprospective trial was to   during 3 weeks for temperature   resin composites varies from1.0%   are free to diffuse out in the oral   is predominantly dependent on the   reactive oxygen species (ROS)  22,34 .
 evaluate the durability of a low   changes and occlusal forces. After 6   to 5.0%  . In the pre-gel phase, the   cavity 13,14 . Adverse reactions may   monomer–polymer conversion. But   Exposure to low con-centrations of
 1
 shrinkage and TEGDMA/HEMA-free   years, 134 Class II restorations were   material is able to flow and stresses   be expected in sensitive operators   in addition, chemical processus   the monomers for a prolonged time
 resin composite system in posterior   evaluated.Twenty-one restorations,   are relieved. Post-gel polymerization   or patients due to the release of   like erosion, enzymatical hydrolytic   reduced the rate of cell proliferation
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 restorations in a 6-year follow up.  8 cmf-els (11.4%) and 13 ASE-els   results in stresses in the material   non-polymerized monomers. Clinical   disintegration and alcoholysis as   possibly as result of DNA damage .
 Methods. 139 Class II restorations   (20%) failed during the 6 years (p   and tooth structures and their   studies have shown that dental resin   well as physical processes like wear   In addition it has been observed that
 were placed in 67 patients with a   < 0.0001). The annual failure rates   interfaces, which may affect the   composites may induce local and   may also contribute to a release   TEGDMA and HEMA are common
 mean age of 53 years(range 29–82).   were 1.9% and 3.3%, respectively.   interfacial adaptation and durability   systematic adverse effects, which   of degradation products from the   sensitizers with a high sensitizing
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 Each participant received at random   The main reasons for failure were   of restorations  2–6 . The magnitude   are caused by methacry-late (co)  polymerized resin in time  . Geurtsen   potential 36–38 . The lower the molecular
 two, as similar as possible, Class II   fracture followed by recurrent caries.   of shrinkage stress depends on   monomers  . Two frequently used   and Leyhausen   concluded that it   weight of the monomer, the higher
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 restorations. In the first cavity of each   Most fractures and all caries lesions   many factors like resin matrix   methacrylatemonomers TEGDMA   should be the aim of future studies   the biophase penetration risk and
 pair the TEGDMA/HEMA-free resin   were found in high risk participants.  formulation, amount of filler used in   (Triethyleneglycol-dimethacrylate)   to replace TEGDMA with more   allergic potential.The risk of allergic
 composite system was placed with   Significance. The Class II resin   the resin composite and degree of   andHEMA (2-hydroxyethyl-  biocompatible diluentmonomers.   reactions increases due to unwary
 its 3-step etch-and-rinse adhesive   composite restorations performed   conversion. Cuspal movement during   methacrylate) eluate from different   HEMA is frequently present in dental   handling of the non-cured resin
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 (cmf-els). In the second cavity a1-  with the newTEGDMA/HEMA-free low   polymerization may be perceived as   resin composites, compomers,   adhesives, resin-modified glass   monomers  . Fast penetration of
 step HEMA-free self-etch adhesive   shrinkage resin composite system   post-operative pain 7–9 . Increasing   resin modified glass ionomers and   ionomers and poly-acid modified resin   uncured monomers through the skin
 was used (AdheSe One F). The   showed good durability over six years.  C-factor may result in greater stresses   adhesives and have been shown   composites. In adhesives, in amounts   and gloves cause contact dermatitis
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 restorations were evaluated using   due to the larger number of bounded   to be responsible for several   from 30% to 55%, it reduces viscosity,   in dental staff  . Patients with
 slightly modified USPHS criteria at   INTRODUCTION  surfaces. Posterior Class I and II   cytotoxic reactions  16–20 . The   promotes diffusion of co-monomers   diagnosed allergies for HEMA and/
 baseline and then yearly during 6   During curing of themonomers, a   cavities will therefore show high stress   diluent monomerTEGDMA show   by expanding the demineralized   or TEGDMA should not receive dental
 years. Caries risk and parafunctional   network of polymers is formed, which   formation. A few low shrinkage resin   biological significant properties,   collagen  24–26  and enhances bond   materials which can release these
 habits of the participants were   becomes rigid due to increasing   composites have been developed and   like low molecular weight, relatively   strength to dentin  . Omission of   monomers. Recently a TEGDMA/
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