Page 187 - 2019秋季手冊內頁-ebook測試
P. 187
衛生福利部雙和醫院(委託臺北醫學大學興建經營)
Results – preliminary overall survival
With a median duration of follow-up of 16.2 months OS plateaus at 84%
衛生福利部雙和醫院(委託臺北醫學大學興建經營)
Discussion - results in perspective
randomized trials OPUS
TAILOR
CALGB 80405 single arm trials APEC
AVETUX
No of patients
72 146 198
110
39
RAS/BRAF
KRAS/BRAFwt RASwt
RASwt
RASwt
RAS/BRAFwt
PTL
uk
left sided left sided
uk
Left sided
ORR (%)
60 66.4 (68.6)*
62.7
81%
ETS >=20% mPFS (%) (months)
69.2 8.3 uk 9.2
11.3 80.6 13.3
76% 11.1
Bokemeyer et al., Ann Onc 2011, Venook et al., JAMA 2017, Qin et al J Clin Oncol 2018, Cheng et al Clin Colorectal Cancer 2017
188
