Page 188 - 2019秋季手冊內頁-ebook測試

衛生福利部雙和醫院(委託臺北醫學大學興建經營)
Translational research
Therapy
Baseline
CRC biopsy and blood
Gene Panel Seq.
week 2 before adding avelumab
week 4
... every 8 wks
Immune Seq.
TR – Predictive value of T cell repertoire TiL and TPS (PD-L1)
衛生福利部雙和醫院(委託臺北醫學大學興建經營)
0.1912
0.1493
25 20 15 10
5 0
mean PFS
25 20 15 10
5 0
mean PFS
TIL low
TIL high
one-sided T-Test
one-sided T-Test
No clear correlation between T cell diversification, TiLs or TPS and PFS likely due to interaction with chemo and EGFRi
189
PFS [months]
PFS [months]