Page 59 - P4403.14_V100_YOUROTC January

SEXUAL HEALTH 59

Not all

erection difficulty

tablets are the same

window window

you decide

when the time is right

Cialis Together 10mg tablets Product Information using machines. Interactions: Patients should not take Cialis Together with nitrate medicines (glyceryl
Presentation: Cialis Together 10mg film-coated tablets containing 10mg of tadalafil. Indications: Erectile trinitrate, isosorbide mononitrate, isosorbide dinitrate), nitric oxide donors (such as amyl nitrite (“poppers”),
dysfunction in adult men. In order for Cialis Together to be effective, sexual stimulation is required. Dose and nicorandil, molsidomine or sodium nitroprusside), riociguat or other guanylate cyclase stimulators. Patient
administration: Men 18 years of age or over: The recommended dose is one 10mg tablet taken at least 30 should consult their pharmacist or doctor before taking Cialis Together with doxazosin and other alpha 1
minutes prior to anticipated sexual activity. The maximum dosing frequency is once per day. Cialis Together adrenergic blockers, 5-alpha reductase inhibitors (e.g. finasteride), antihypertensives, other treatments for
is not recommended for continuous daily use. Contraindications: Hypersensitivity to the active substance or erectile dysfunction, theophylline, ethinylestradiol or terbutaline. CYP3A4 inhibitors such as ketoconazole,
to any of the excipients, co-administration with nitric oxide donors or nitrates, cardiac disease in patients itraconazole, erythromycin, clarithromycin, cimetidine, and grapefruit juice should be administered with
where sexual activity is inadvisable, myocardial infarction within the last 90 days, unstable angina or angina caution as they may increase the incidence of adverse reactions. CYP3A4 inducers such as rifampicin,
during sexual intercourse, NYHA class 2 or greater heart failure in the last 6 months, uncontrolled arrhythmia, phenobarbital, phenytoin and carbamazepine may decrease plasma concentrations of tadalafil and
hypotension (< 90/50 mm Hg), uncontrolled hypertension, stroke within 6 months, non-arteritic anterior decrease efficacy. Pregnancy and breastfeeding: Cialis Together is not indicated for use in women. Adverse
ischaemic optic neuropathy causing loss of vision in one eye, co-administration with guanylate cyclase Reactions: Adverse events observed from spontaneous reporting and clinical trials: Common (≥1/100
simulators (e.g. riociguat), deformation of the penis (such as angulation, cavernosal fibrosis or Peyronie’s and 1/10): Headache, flushing, nasal congestion, dyspepsia, back pain, myalgia, pain in extremity. Uncommon
disease), women, those without erectile dysfunction and men under 18 years of age. Warnings and (≥1/1,000 and 1/100): Hypersensitivity reactions, dizziness, blurred vision, eye pain, tinnitus, tachycardia,
precautions: All men with erectile dysfunction should be advised to consult their doctor within 6 months for a palpitations, hypotension, hypertension, dyspnoea, epistaxis, abdominal pain, vomiting, nausea,
clinical review of potential underlying conditions and risk factors associated with erectile dysfunction. If gastro-oesophageal reflux, rash, haematuria, prolonged erections, chest pain, peripheral oedema, fatigue.
symptoms of erectile dysfunction have not improved after taking Cialis Together on several consecutive Rare (≥1/10,000 and 1/1000): Angioedema, stroke (including haemorrhagic events), syncope, transient
occasions or if their erectile dysfunction worsens patients should consult their doctor. Patients who have ischaemic attacks, migraine, seizures, transient amnesia, visual field defect, swelling of eyelids, conjunctival
undergone pelvic surgery or radical non nerve sparing prostatectomy or with known hereditary degenerative hyperaemia, non-arteritic anterior ischemic optic neuropathy, retinal vascular occlusion, sudden hearing
retinal disorders (e.g retinitis pigmentosa) should consult their doctor before taking Cialis Together. Patients loss, myocardial infarction, unstable angina pectoris, ventricular arrhythmia, urticaria, Stevens-Johnson
with cardiovascular disease should be advised that sexual activity carries a cardiac risk and if they syndrome, exfoliative dermatitis, hyperhydrosis, priapism, penile haemorrhage, haematospermia, facial
experience chest pain during sexual activity they should refrain from any further sexual activity and seek oedema, sudden cardiac death. RRP (ex VAT): 8 tablets pack: £31.66, 4 tablets pack: £18.33. Legal category: P.
medical attention immediately. Cialis Together is not recommended for patients who experience chest pain Licence number: PL 53886/0076. Product licence holder: Sanofi, 410 Thames Valley Park Drive, Reading,
or breathlessness after light or moderate activity. Patients should consult their doctor before resuming sexual Berkshire, RG6 1PT, UK. Further information is available from Sanofi, 410 Thames Valley Park Drive, Reading,
activity if they have: uncontrolled hypertension, moderate to severe valvular disease, left ventricular Berkshire, RG6 1PT. Email: uk-medicalinformation@sanofi.com
dysfunction, hypertrophic obstructive and other cardiomyopathies, significant arrhythmias, had coronary Document number: MAT-XU-2302378 v1.0 Date of preparation: June 2023.
artery bypass surgery or angioplasty, asymptomatic controlled hypertension, mild valvular disease. Patient
with an increased susceptibility to vasodilators including patients with left ventricular outflow obstructions
Adverse events should be reported. Reporting forms and information can be found at
(e.g. aortic stenosis) or multiple atrophy should consult their doctor before taking Cialis Together. Patients
www.mhra.gov.uk/yellowcard. Adverse events should also be reported to the Sanofi drug safety
should check with their doctors before taking Cialis Together with doxazosin and other alpha blockers. In case department on 0800 0902522
of sudden visual defect or sudden decrease or loss of hearing patient should stop Cialis Together and seek
medical attention immediately. Patients with severe renal impairment and severe hepatic impairment
should consult their doctor before taking Cialis Together. Patients who experience erections lasting 4 hours or MAT-XU-XXXXX (v1.0) September 2024
more should seek immediate medical assistance. Patients who have conditions which may predispose them
to priapism (such as sickle cell anaemia, multiple myeloma or leukaemia), should consult a doctor before
taking Cialis Together. Cialis Together should not be used in a patient who has an anatomical deformation of
the penis. Patients taking potent CYP3A4 inhibitors should consult a doctor before taking Cialis Together.
Patients should avoid drinking excessive amounts of grapefruit juice. The use of Cialis Together with other
treatments for erectile dysfunction is not recommended. Patients should not drink large amounts of alcohol Buying POR
before sexual activity. Use of Cialis Together with recreational drugs (including but not limited to “poppers”, Product Size Price/ RRP Pip Code
nitrous oxide, GHB/GBL, methamphetamines, MDMA/ecstasy, ketamine, flunitrazepam, cannabis, opioids, Single %
cocaine, etc.) may lead to adverse events such as dizziness, decrease of blood pressure, stroke or heart
attack, seizures, priapism, and coma. Cialis Together contains lactose; Patients with rare hereditary problems CIALIS
of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take
Cialis Together. Effects on ability to drive and use machines: Cialis Together has negligible influence on the CIALIS TOGETHER 4 PACK 4 £11.03 £21.99 40% 4237467
ability to drive or use machines. Although the frequency of reports of dizziness in placebo and tadalafil arms
in clinical trials was similar, patients should be aware of how they react to Cialis Together, before driving or CIALIS TOGETHER 8 PACK 8 £19.05 £37.99 40% 4237475
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