Page 43 - ANZCP GAZETTE DECEMBER 2023

MULTIPLE CHOICE 7
Sreenivasulu Galaeti CCP (Aus), CCP (Ind)
1. In sickle cell patients tendency for sickling occurs with ___________?
a) Hypoperfusion and capillary stagnation.
b) Hypoxemia (blood O2 saturation less than 85%)
c) Acidosis or increased levels of 2,3-DPG
d) Hypothermia or Infection.
e) All of the above
2. Hemophilia A, Hemophilia B, Hemophilia C are caused by a lack of _____, ______, and ______
a) Factor VIII, Factor IX, and Factor XI.
b) Factor VII, Factor VIII and Factor IX.
c) Factor VIII, Factor IX and Factor X.
d) Factor IX, Factor X and Factor XI.
3. Increasing the oxygen level decreases the affinity of hemoglobin for carbon dioxide, this is called ________ effect.
a) Haldane
b) Bohr
c) Raman
d) None of the above.
4. Concerning the blood supply of the liver:
a) The hepatic artery inflow and hepatic venous drainage do not communicate across left and right halves of the liver.
b) The portal vein has a Y-shaped division into left and right
portal vein branches in the porta hepatis.
c) The hepatic ducts in the porta hepatis lie in front of the
branches of the hepatic artery and portal vein.
d) The quadrate and caudate lobes receive their major blood supply from the right hepatic artery and right portal vein.
5. The middle colic artery is a branch of the:
a) Superior mesenteric artery
b) Inferior mesenteric artery.
c) Coeliac trunk.
d) Common hepatic artery.
e) Left gastric artery.
6. The primary physiological action of insulin is to increase:
a) Glycogen synthesis by the liver
b) Lipid synthesis by the liver and fat depots
c) Glucose uptake by the brain
d) Glucose uptake by the muscles
e) Protein synthesis
7. An intrinsic mechanism for increasing the force of contraction of heart muscle involves:
a) Stimulation of sympathetic nerves emanating from the stellate ganglion.
b) Regulation of myofilament Ca ++ sensitivity by altered resting length.
c) Increased contractility via phosphorylation of troponin I.
d) Reduced phosphorylation of the plasma membrane Ca
pump by cGMP.
e) cAMP-dependent phosphorylation of L-type Ca ++ channels.
8. An increase of neuronal activity in the brain is linked to increased O 2 consumption. The cellular pathway for this phenomenon involves:
a) Astrocytes Neurons smooth muscle
b) Neurons Astrocytes smooth muscle
Endothelial cells Endothelial cells
Arteriolar Arteriolar Arteriolar
c) Endothelial cells smooth muscle
Neurons
Astrocytes
d) Arteriolar smooth muscle Endothelial cells Astrocytes
Neurons Aarteriolar smooth muscle
e) Endothelial cells Astrocytes neurons
9. The radius (r) of an arteriole is reduced to 1⁄2 of its original value by an atherosclerotic plaque. Assuming all other factors are unchanged, what will flow (Q) be under this condition?
a) Increased by 1⁄16 of original flow b) Decreased by 1⁄2 of original flow c) Unchanged
d) Increased to 1⁄2 of original flow
e) Decreased to 1/16 of original flow
10. The effect which is LEAST likely to occur shortly after transfusion of 25U of whole blood:
a) Hypocalcaemia
b) Dilutional coagulopathy
c) Metabolic alkalosis
d) Increased affinity of Hb for O2 e) Hyperkalaemia
f) Metabolic acidosis
g) Coagulopathy
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