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Wound Care Glossary


          Term               Description
          Abrasion           Wearing away of the skin through some mechanical process (friction or trauma).
          Abscess            Accumulation of pus enclosed anywhere in the body.
          Antibiotic         Pharmacologic agents that destroy or inhibit bacteria. May be broad or narrow in spectrum of activity.
                             May be used systemically and topically.
          Antifungal         Pharmacologic agents that inhibit the growth of fungal infections.  May be broad or narrow in spectrum of
                             activity. May be used systemically and topically.
          Antimicrobial      Any agent that destroys or inhibits the growth of microbes including bacteria, fungi, viruses, or protozoa
          Antiseptic         Chemical agents that prevent, inhibit, or destroy microorganisms including bacteria, viruses, fungi,  and
                             protozoa. Topical use only.
          Autolysis          Disintegration or liquefaction of tissue or cells by the body’s own mechanisms, such as leukocytes and
                             enzymes.
          Bacterial load     Total number of bacteria in a wound; may or may not cause a host response.
          Bacteriostatic     Agent capable of inhibiting the growth of bacteria.
          Biofilm            Polysaccharide matrix that microorganisms produce; highly resistant to antimicrobials. Must be removed
                             by debridement.
          Bioburden          Presence of microorganism on or in a wound. Continuum of bioburden ranges from contamination,
                             colonization, critical colonization, biofilm and infection. Bioburden includes quantity of microorganism
                             present, as well as their diversity, virulence, and interaction of the organism with each other and the body.
          Blanching          Becoming white; maximum pallor
          Cellulitis         Inflammation of the tissues indicating a local infection; characterized by redness, edema, and tenderness

          Collagen           Main supportive protein of the skin.
          Colonization       Presence of replicating bacteria that adhere to the wound bed but do not cause cellular damage to the
                             host.
          Contamination      Non‐replicating microorganisms on the wound surface without a host reaction. All open wounds are
                             contaminated by normal skin flora.
          Critical           Increasing bacterial load on a wound that is between the category of colonization and infection. Wound
          colonization/Local   does not heal but may not display classic signs of infection.
          infection
          Dead space         Defect or cavity
          Debridement        Removal of foreign material and devitalized or contaminated tissue from a wound until healthy tissue is
                             exposed.
          Decubitus          Latin word referring to the reclining position; misnomer for a pressure sore.
          Demarcation        Line of separation between viable and nonviable tissue.
          Denuded            Loss of epidermis
          Disinfectant       Topical liquid chemical that destroys or inhibits growth of microorganisms.
          Enzymes            Biochemical substances that are capable of breaking down necrotic tissue.
          Epithelialization   Process of the formation of new epithelial tissue‐upper layer of the skin.
          Erosion            Loss of epidermis
          Erythema           Redness of the skin surface produced by vasodilation.
          Eschar             Thick, leathery, black or brown crust; can be loose or firmly adherent, hard or soft, dry or wet; it is
                             nonviable tissue and is colonized with bacteria.
          Excoriation        Linear scratches on the skin.  NOT redness or denuded.
          Exudate            Accumulation of fluid in a wound; may contain serum, cellular debris, bacteria, and leukocytes.
          Fistula            Abnormal passage from an internal organ to the body surface or between two internal organs.
          Friction           Rubbing that causes mechanical trauma to the skin.
          Full‐thickness     Tissue destruction extending through the dermis to involve subcutaneous level and possibly muscle, fascia,
                             or bone.
          Granulation        Formation of connective tissue and many new capillaries in a full‐thickness wound; typically appears as red
                             and cobblestoned. Occurs only in a full‐thickness wound.
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