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MANAGEMENT OF ERECTILE DYSFUNCTION


             _________________________________________Management of  Bipolar Disorder (Second Edition)
             _________________________________________Management of  Bipolar Disorder (Second Edition)
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             _________________________________________Management of  Bipolar Disorder (Second Edition)
             __ __ __ _ __ _ __ _ __ _ __ __ _ _ __ __ __ _ __ TABLE OF CONTENTS   o f    Bi p o l ar  D i so r d er  (Sec o n d  E d i ti o n )
             No.                    TABLE OF CONTENTS                Page
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             No.  .    Levels of Evidence and Formulation of Recommendation     Page
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                                        Title
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                 Levels of Evidence and Formulation of Recommendation
                                                                      i

                 Key Recommendations

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                 Levels of Evidence and Formulation of Recommendation
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                 Key Recommendations

                                                                      ii

                                                                      iv
                 Guidelines Development and Objectives
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                 Key Recommendations
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                                                                      ii  vi ii

                 Guidelines Development and Objectives
                                                                      iv

                                                                      vi
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                                                                      vii
                 Development Group

                                                                      vi
                 Review Committee

                                                                      vii
                          t
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                 Development Group
                 D
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                                                                      vii
                                                                     viii
                 External Reviewers
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                 Review Committee
                            ee
                                                                      vii  x vii
                 External Reviewers
                                                                     viii
                 Algorithm 1: Treatment of Acute Mania
                                                                      ix
                           w
                       R
                                                                      xi

                                                                     viii
                          i
                                                                     v
                 External Reviewers
                 E
                          e
                        ev
                  xternal
                            ers
                 Algorithm 1: Treatment of Acute Mania
                                                                      ix
                 Algorithm 2: Treatment of Acute Depressive Episode
                                                                      x
                    ri
                                                                      ix  ix
                           reatm
                      hm
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                 A
                  l
                        1:
                 Algorithm 1: Treatment of Acute Mania
                          T
                                                                      xii

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                 Algorithm 2: Treatment of Acute Depressive Episode
                                                                      x

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                                    A
                        2:
                 A
                 Algorithm 2: Treatment of Acute Depressive Episode
                                  of
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                                                                      x  x

                 INTRODUCTION
                                                                      1

                                                   1.   Review Committee      en t t     of     A cu t t e M an i a    siv e Ep i so de    xiii i         i i
                                                                      1
                 INTRODUCTION
              1.

                 N
              1
              1.  .      I INTRODUCTION                               1  1
                          O
                  T
                       U
                    O
                   R
                          I
                         T
                        C
                     D
                           N


              2.   RISK FACTORS                                       1


              2.   RISK FACTORS                                       1


              2
              2.  .    R I S K   F A C T O R S                        1  1
                 RISK FACTORS

              3.     SCREENING AND DIAGNOSIS                          2

              3.       SCREENING AND DIAGNOSIS                        2
                 3.1 Screening Tools
                                                                      2
                 SCREENING AND DIAGNOSIS
              3 3.  .    S C R E E N I N G   A N D   D I A G N O S I S    2  2
                 3.2 Differential Diagnoses
                 3.1 Screening Tools                                  2
                                                                      4
                 3.1 Screening Tools
                 3.2 Differential Diagnoses
                 3.1  S creen i ng   T oo l s                         2  2
                                                                      4
                 3.3 Co-Morbidities
                                                                      5
                               no
                         i
                                 s
                             i
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                                 e
                            D
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                 3.2
                       rent
                          al
                             ag
                   3.2 Differential Diagnoses                         4  4
                                                                      5
                 3.3 Co-Morbidities
                   3.3 Co-Morbidities                                 5  5
                   C
                     -
                 3.3
                      M
                           t
                          di
                            es
                         i
                            i
                       orb
                    o

              4.     TREATMENT                                        6


               4.   TREATMENT                                         6
                                                                      6
                 4.1 Pharmacotherapy
                     T
                        N
                 T
                   E
                       E
                  R
                         T
                    A
                      M
                                                                      6
                         4 4.  .    TREATMENT    t he rapy            6  6
                 4.1 Pharmacotherapy
                       4.1.1 Manic Episode
                                                                      6
                    ha
                 4.1
                 4.1 Pharmacotherapy
                                                                      6  6
                      r
                       maco
                   P
                                                                      6
                       4.1.1 Manic Episode
                       4.1.2 Depressive Episode
                                                                      8
                        an
                             pisod


                          i

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                   4
                                 e
                     1.1


                    .
                       4.1.1 Manic Episode


                            E
                       M

                       4.1.2 Depressive Episode
                                                                      8
                                                                      9


                       D
                          ress
                    .
                                                                      8  8
                                         4.1.3 Bipolar disorder with specifiers   6  6
                                    de
                             v

                       4.1.2 Depressive Episode
                        ep



                                  so

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                     1.2

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                               4.1.3 Bipolar disorder with specifiers
                                                                      9
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                               4.1.3 Bipolar disorder with specifiers
                                   w

                                   4.1.4 Maintenance phase  t T   h N rap i N R A   E r   T i i F f ng R s M   R   T ain L E t   e R na P nc E e Ph as e    12
                                                                     12
                               4.1.4 Maintenance phase
                 4.2 Non-Pharmacological Therapy

                                                                     15
                               4.1.4 Maintenance phase
                                                                     12

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                 4.2 Non-Pharmacological Therapy

                                                                     15
                                                                     15
                       4.2.1 Physical therapy

                 4.2
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                 4.2 Non-Pharmacological Therapy
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                                                                     15
                                                                      5
                                                                     1 16
                       4.2.1 Physical therapy
                                                                     15

                       4.2.2 Psychosocial intervention
                                                                     18

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                                                                     1 16

                       4.2.1 Physical therapy


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                                                                     15
                                                                      5
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                                                                     18
                       4.2.2 Psychosocial intervention

                       4.2.3 Psychotherapy

                                                                     19
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                                                                     18
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                       4.2.2 Psychosocial intervention


                       4.2.3 Psychotherapy

                                                                     19






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                       4.2.3 Psychotherapy
                                 y

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                                                                     1
                                                                      9
                                                                     19



             5.
                                                                     21
                 COMPLEMENTARY AND ALTERNATIVE THERAPIES



                                                                     21
             5.
                 COMPLEMENTARY AND ALTERNATIVE THERAPIES



                 C
                 COMPLEMENTARY AND ALTERNATIVE THERAPIES
                                           V
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                                                                     21
                           A
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             5
             5.
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                 FOLLOW-UP/MONITORING AND REFERRAL
                                                                     21
             6.



                 FOLLOW-UP/MONITORING AND REFERRAL
             6.
                                                                     21
                                                                     21
                 6.1 Parameters to be Monitored during Maintenance Phase

                                 I
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                 FOLLO
                 FOLLOW-UP/MONITORING AND REFERRAL
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             6.
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                 6.1 Parameters to be Monitored during Maintenance Phase
                                                                     21

                 6.2 Referral Criteria
                                                                     22
                                                                     21
                                                                     2
                 6.1 Parameters to be Monitored during Maintenance Phase
                         e
                 6.1
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                 6.2 Referral Criteria
                                                                     22



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                 6.2 Referral Criteria
                         l

                 6.2
                   R
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                                                                     22
                                                                     22


             7.
                                                                     22
                 RELAPSE PREVENTION AND ADHERENCE
                                                                     22
                 7.1 Prevention of Relapse

                                                                     22
                                                                     2
                    A
                                           E
                 R
                                     D
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                            E
                                 N
             7.
                                         E
                                        H
                                      A
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             7
                                  A
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                 RELAPSE PREVENTION AND ADHERENCE
                              T
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                                            N
                                                                     22

                 7.1 Prevention of Relapse

                 7.2 Strategies to Improve Adherence
                                                                     23
                 7.1 Prevention of Relapse
                 7.1
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                                                                     22
                         i
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                                                                     23
                 7.2 Strategies to Improve Adherence
                                                                     25

                 7.3 Collaborative Care Models
                                 v
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                 7.2
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                 7.2 Strategies to Improve Adherence
                           t
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                                                                     23
                    t

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                 7.3 Collaborative Care Models
                                                                     25


                 7.3 Collaborative Care Models
                           i
                 7.3
                                                                     2
                                                                     25

                          t
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                 SPECIAL POPULATIONS
                                                                     26
             8.


             8.
                 SPECIAL POPULATIONS
                                                                     26

                 8.1 Pregnancy and Lactation
                                                                     26
                                                                     26
             8
                                                                     2
             8.
                                  S
                   E
                    C
                                N
                 S
                 SPECIAL POPULATIONS
                  P

                      L POPU
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                             A
                     A
                               O
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                 8.1 Pregnancy and Lactation

                                                                     26

                                                                     27
                 8.2 Elderly

                 8.1 Pregnancy and Lactation
                   P
                             d Lac
                    regn
                 8.1

                                                                     2
                                                                     26
                                 t
                                  ati
                                   on
                           an
                         cy
                        an

                 8.2 Elderly
                                                                     27

                                                                     28

                 8.3 Children and Adolescents

                 8.2 Elderly
                   E
                 8.2


                     de
                       y
                                                                     2
                                                                     27
                    l
                      rl
                 8.3 Children and Adolescents
                                                                     28


                                                                     30
                 8.4 People with Substance Use Disorder


                                                                     28
                    hi
                      dren
                            d
                      l
                              do
                             A
                                                                     2
                 8.3 Children and Adolescents
                 8.3
                   C
                                    nts

                          an
                                l
                                es
                                  ce
                                                                     30

                 8.4 People with Substance Use Disorder
             _________________________________________Management of  Bipolar Disorder (Second Edition)
                              bs
                                          rder
                    eo
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                                a
                                      e Diso
                   7.  . .        RELAPSE PREVENTION AND ADHERENCE     2 2       2 2 3   5       6 6 7 8 0
                           h Su
                          t
                         w
                       e
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                   P
                                                                     3
                 8.4
                                 nc
                 8.4 People with Substance Use Disorder
                                                                     30
                                   e Us

                 8.5 People with Borderline Personality Disorder      31


              9.   SUICIDE PREVENTION                                 31
                 9.1 Risk and Protective Factors   iii                31
                 9.2 Effective and Safe Intervention                  32

             10.  IMPLEMENTING THE GUIDELINES                         33
                 10.1 Facilitating and Limiting Factors               33
                 10.2 Potential Resource Implications                 34

                 REFERENCES                                           35

                 Appendix 1   Example of Search Strategy              42
                 Appendix 2   Clinical Questions                      43
                 Appendix 3   Diagnostic  Criteria  of  Bipolar  Disorder  based  on   44
                            Diagnostic and Statistical Manual of Mental Disorders
                            Fifth   Edition,   Text   Revision   (DSM-5-TR)   or
                            International  Classification  of  Diseases  Eleventh
                            Revision (ICD-11)
                 Appendix 4   List of Screening Tools in Bipolar Disorder   47
                 Appendix 5   Recommended  Adult  Medication  Dosages  and   48
                            Adverse Effects for Bipolar Disorder
                 Appendix 6   Psychoeducation for Bipolar Disorder    56
                 Appendix 7   Parameters for Monitoring during Treatment of Bipolar   57
                            Disorder
                 Appendix 8   Collaborative Care Model Core Elements   59
                 Appendix 9   Summary  of  Medications  for  Bipolar  Disorder  in   60
                            Pregnancy and Lactation
                 Appendix 10a  Annual Risk Acknowledgement Form       66
                 Appendix 10b  Borang Pengakuan Risiko Tahunan        68
                 Appendix 11   Suggested Paediatric Medications Dosing   70

                 List of Abbreviations                                75
                 Acknowledgment                                       77
                 Disclosure Statement                                 77
                 Source of Funding                                    77
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