Page 10 - Basco Scientifics Profile & Products_Neat

Cross Flow Filtration Bioprocess Bags/Liners Totes/Trays For Bags
Modules/System BioProcess Bags & Liners are optimized The ALLpaQ® Cleanroom range is
for specific container applications. currently available in 250-L, 500-L,
Tangential flow membrane technology
spans both microfiltration(MF) and Bags provide maximum flex-cracking and 1,000-L units. As with the
ultrafiltration (UF) separations. resistance, strength and durability and Genesis, Custom, and Top drain
Membrane technology for MF are well suited for cell culture range, they offer customers a degree
separationsinclude retention applications. Each container product is of flexibility to ensure that units can
ratings of0.5 µm, 0.2 µm, 0.1 µm constructed using NxFlex F1000C1 film, be optimized for the bag of choice
and 0.05 µm.UF technology includes and therefore eliminate the need for
a medical grade multi-layer film
membranes withMWCO ratings of time-consuming bag revalidations
1,000 kD, 400 kD, 50kD and 10 kD. specifically designed for high and minimizing disruption to
performance bioprocess applications. operatins
The hollow fibers are cast from either Bag utilizes both RF and Heat Impulse
Polysulfone (PS), mixed cellulose ester Sealing depending on the size and type
(ME), Polyethersulfone (PES) or
of bag. The bags & Liners are typically
Polyvinyl difluoride (PVDF) with
have ports on one end and handles on
fiber diameters of0.5 mm and 1 mm.
the opposing end. Offers one and
From these uniformhollow fibers,
Ffiltration modules are constructed three port designs.
into severalconfigurations with BioProcess Bags are used in a variety
effective membranesurface areas of applications such as:
ranging from 5 cm2 up to 3.3 m2
 Buffers and media storage
Applications:  Harvest collection
 Cell Concentration,  Storage and transport
Clarification and Diafiltration  Intermediate process containers
 Lysate Clarification  Ultrafiltration ,Diafiltration
 VLP and Virus Concentration applications
and Diafiltration  Chromatography fraction collection
 VLP and Virus Clarification
 Protein Purification, The film construction of NxFlex
F1000C1 consists of several layers of
Concentration and Diafiltration Aseptically Connect
 NanoParticle and Latex Particle biologically compatible polyethylene : Aseptically Disconnect
combined with a gas impermeable
Diafiltration and Fractionation layer of ethylene vinyl alcohol (EVOH).
 Bacteria Concentration and The fluid contact layer is a blend of OmniTop Sample Tubes® can be
aseptically connected to your
Diafiltration EVA and LLDPE. The combination of bioreactor or other device using
 Liposome, siRNA films and their composition create a standard tubing welders, such as the
structure that is highly resistance to
Concentration and Diafiltration Terumo SCD-IIB. Sample Tubes can also
stress cracking, punctures, and pin-
be aseptically sealed and removed (wet
hole damage.
or dry) using tubing sealers such as the

Genesis SE340 or handheld battery
powered version SE640.

Application(s):
 Transfer of biopharmaceutical products
and reagents in a closed system
 Gas exchange transfer
 Sampling of biopharmaceutical
products and reagents in a closed

system
 Storage of biopharmaceutical products
and reagents
 Use with bench top, pilot plant, and
production bioreactors
 Use with sterile connecting devices and
thermal or RF tubing sealers``