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12 Methanosarcina barkeri Precorrin- Uroporphyrinogen III Methylation S-adenosyl-L-methionine (Buchenau , 2006 (Monoxide dehydrogenase) Hydrogenase) Methyl coenzyme M reductases) Mamimin 2019 (Ni Co Fe Ni/Co/Fe 90.4 139 (Hydrogenase) (hydA Ni/Co/Fe 21.7 454 Ni/Co/Fe Bacillus sp., Thermoanaerobacterium sp Clostridium sp. Methanomassiliicoccus sp. Methanosarcina sp. Methanoculleu sp 7.11)