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36. Bacterial Protein

synthesis inhibitors

Protein synthesis inhibitors

Broad Moderate
2
spectrum (TC) spectrum (KM) Short spectrum (L S)

Chloramphe Streptogram
Tetracyclins Macrolide Ketolide Lincosamide Linezolide
nicol ins

Mechanisms

Tetracycline

Tetracycline  tRNA  tries but cannot bind

 Prevent the amino acyl transfer RNA from attaching A site on
ribosome.

ChloramPhenicol

Chloram + Phenicol  Phenicol  Peptide
Contents  Inhibit the peptide bond formation by peptidyl transferase

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman