Page 56 - Pharmacology Mnemonics and Short Notes
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               Nicotinic N  ANS ganglia
               nicotinic M  neuromuscular end plate (M for muscle)

                                                  +
                                                      +
               Mechanisms: they act on Na -K ion channels  depolarize and
               evoke action potential

        Adrenergic Receptors



                 England  alpha 1 in effector tissues

                 Never  alpha 2 in Nerve endings
                   and smooth muscles


                 Have  beta 1 in heart

                 Some  beta 2 in smooth muscles


                 Apology beta 3 in adipose tissue

        Dopamine D1 receptor in renal vascular smooth muscles

        Mechanisms:


               First alpha 1  increases IP3 DAG (like M 1)

               Second alpha 2  decreases cAMP (like M 2)

               Rest betas and dopamine receptors all increase cAMP


                                      Adrenergic transmission


















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   Pharmacology Mnemonics and Short Notes                                              By Muhammad Ramzan Ul Rehman
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