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Oculocutaneous Albinism
Oculocutaneous Albinism (OCA) is a condition seen in Angus cattle. It affects the
black coat color to change it to a coppery red tinged black, but the main effect of
this recessive condition is an eye abnormality. The eye looks abnormally white.
The animal avoids sun and it is assumed this condition makes it quite
uncomfortable to be in the sun. Shade must be available in the form of trees or a
shed for such animals.
Preliminary data suggests that this is not a tyrosinase mutant nor a tyrosinase
related protein 1 mutant based on examination of genomic coding sequence. OCA
exists in at least 3 forms in humans and these two genes are implicated in OCA-1
and OCA-3 or ROCA.
