Page 30 - Chow Life - Winter 2017
P. 30

Saving Litters From




                 Canine Herpes



                                                                                             By Jeff Grognet, DVM


            Canine herpesvirus (CHV) only     they do not have any immunity to the   creating hemorrhage and tissue
          affects members of the canine       virus.                             death in the kidneys, lungs, liver, and
          family—dogs, coyotes, and wolves. It   The incubation period in puppies   intestines. This is why clinical signs
          was first reported in 1965. When it   (time from infection to clinical signs)   of CHV in puppies are so varied.
          strikes, it is devastating. What many   is four to six days. If whelping is   They include depression, diminished
          breeders don’t realize is that the virus   some time off, we can see infection   suckling responses, persistent
          is common in the canine population,   of the placenta (placentitis) resulting   crying, diarrhea, rhinitis (nose
          latent in many dogs. This allows it to   in abortion. Mummification of the   infection), severe abdominal pain, and
          come out of hiding, infect susceptible,   fetuses, stillbirths, and premature   incoordination. Neurologic signs such
          pregnant bitches, and cause stillbirths   births can also occur.       as seizures may appear just before
          or neonatal puppy deaths.                                              death. Puppies normally die within
                                               Puppies infected later in gestation
            CHV is easily spread between dogs   can be born with the virus, but die   24 to 48 hours of the onset of clinical
          by licking (saliva and nasal mucus)   shortly after birth. They can also   signs.
          or coughing (aerosol). It can also be   become infected in the first three    Though rare, puppies sometimes
          passed through the uterus to pups,   weeks of life (they seem immune after   survive the initial infection but the
          and venereally to other dogs.       this period) and go on to die.     virus can move into brain tissues.
            Dogs can harbor the virus in their   In a study where seven pregnant   This can trigger meningitis, but we
          trigeminal nerve (the large nerve that   bitches were infected between days   can also see deafness, blindness, and
          supplies the face). It comes out of   47 and 55 of gestation, 28 pups (of   encephalopathy.
          hiding if the dog is stressed or receives   33 total) were infected. Two were
          corticosteroids like prednisone. Cold
          sores in people infected with the
          human strain of herpesvirus erupt in    CHV is easily spread between
          a similar manner. The two do not pass
          between species.
            Mature (non-pregnant) dogs who                        dogs by licking.
          pick up CHV infections usually have
          mild symptoms of the nose, throat,
          and external genitalia (vagina or   stillborn, and 26 died in the early   Diagnosis & Treatment
          prepuce), or no symptoms at all.    neonatal period. The remaining five   Clinical signs of CHV are the same
          Male dogs can sometimes develop a   stayed healthy.                    as almost any other disease that
          balanoposthitis (penile infection). The   There are two reasons why young   strikes newborn puppies, and causes
          penile tissue is reddened with small   puppies are particularly susceptible   fadingpuppy syndrome. If an entire
          hemorrhages on the surface combined   to the effects of CHV. One is that   litter is lost in a 24-hour period, CHV
          with a clear preputial discharge.   their immature immune systems      should be considered as a cause. Also,
                                              can’t fight off the infection. As well,   if any puppy has signs of an upper
          The Peril For Pups                  they are unable to regulate their   respiratory infection and is less than 2
            The problem arises when bitches   body temperature properly. This    months old, CHV could be the culprit.
                                              becomes important because the virus
          become infected during the last three   prefers to multiply at a temperature   The only way to know if CHV is at
          weeks of pregnancy. They usually    of 99 degrees F. As puppies age, they   the root of the deaths is with tests.
          remain healthy, but they pass the virus   keep their body temperature higher   This can be done by finding typical
          to their puppies through the placenta   (around 101.5) so the virus can’t grow   lesions on post mortem (multi-
          or directly to them after being born.   as fast.                       organ damage evidenced by small
                 Young, susceptible females                                      hemorrhages) and then isolating
                 and their newborn puppies     In puppies, the virus attacks     the virus from the aborted fetus and
                 are at the greatest risk because   whatever organ system it wants,   placenta, or the dead puppy. If the
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