Page 34 - Chow Life - Summer 2016 Issue
P. 34

areas. This can then overgrow          those hormones and that may vary              adverse side effects and careful
  under hormonal influence and may       with each heat.” Pyometra may                 monitoring is necessary. They
  cause cysts to form in a condition     affect bitches of any age following           should not be used in closed
  known as cystic endometrial            estrus, but it is seen more often             pyometra, as it may cause
  hyperplasia (CEH). With each cycle,    in mature bitches due to many                 uterine rupture. Treated
  hyperplasia waxes and wanes as         years of CEH buildup. Because                 bitches have reduced fertility
  the bitch repeats the estrous cycle    Missy was not bred for almost                 and the chance of recurring
  and it is this process that can lead   three years, CEH could have begun             pyometra is very high (50 to
  to pyometra. The mucus secreted        before her first litter, building             75 percent). The bitch must be
  by the cysts that form over time       during the following cycles,                  bred at every cycle thereafter
  inflames the uterine lining, helping   providing ripening conditions for             to prevent reoccurrence of
  to make conditions right for           finally developing pyometra at 5              pyometra. The U.S. Food and
  bacteria to multiply out of control.   years. Natural breeding, artificial           Drug Administration (FDA),
  After ovulation, progesterone          insemination, or a urinary-                   however, has not approved
  decreases the response of white        tract infection can introduce                 these drugs for treatment
  blood cells to sperm to aid in         variably infective bacteria into a            of canine pyometra in this
  fertilization, but consequently,       susceptible uterus. Administration            country. Threlfall says that
  this action lets the guard down        of estrogen to prevent pregnancy              in the United States the
  for killing bacteria that may enter    after a “mismating” or to delay               treatment of bitches with a
  the open cervix. Progesterone also     heat presents a significant risk of           combination of antibiotics and
  decreases uterine contractions and     pyometra.                                     prostaglandin F2- alpha is an
  closes the cervix, keeping sperm                                               acceptable practice, and he has used
  inside the uterus and trapping         Alternate Treatments                    it since 1980. Lack of FDA approval
  the bacteria there as well. They                                               is a funding, not a safety issue, he
  grow hidden and quickly within           By the time pyometra is               believes, and he treats stabilized
  the inflamed lining, nourished by      diagnosed, future breeding is           bitches who are not severely toxic. If
  mucus and protected from body          questionable. If pyometra is caught     you do not plan to breed your bitch,
  defenses. Walter R. Threlfall, DVM,    early, and the bitch is valuable for    spaying is the best way to avoid
  is a theriogenologist (reproductive    breeding, some breeders may opt to      pyometra. The incidence of this
  specialist) at the Department of       treat it with antibiotics. This is not  disease increases with time, and the
  Veterinary Clinical Sciences, The      highly successful because infection     cost of spaying is much less than the
  Ohio State University. He says,        will continue unless uterine pus is     emotional cost of losing a beloved
  “Endometrial hyperplasia probably      purged. In countries outside the        pet to a preventable disease. If she
  occurs in all bitches, but the degree  United States, treatment includes       is an asset to her breed and you
  to which it occurs varies. It isn’t    antibiotics in conjunction with         plan litters, be sure to check for
                                         prostaglandins to force uterine         symptoms of pyometra, particularly
         based on the concentrations     contractions to expel the infected      after each estrus, whether she is
         of the hormones, but on         contents, but these drugs can cause     bred or not. When her breeding
         how each bitch ‘deals’ with                                             days are over, have her spayed. Be
32                                                                               sure to discuss these options with
                                                                                 your veterinarian.

                                                                                 Beverly Stanley is a medical editor and
                                                                                 writer who has bred and exhibited Silky
                                                                                 Terriers and Papillons for over 30 years and
                                                                                 currently shows a Toy Fox Terrier.
                                                                                 This article first appeared in the April 2011
                                                                                 issue of the AKC GAZETTE and is reprinted
                                                                                 with permission.
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