Page 40 - חוברת תזות הנדסה ירוקה 2023

be the result of a change in a small subunit lacking catalytic activity, which, when mutated, gives rise to modifications in the catalytic pocket, enabling prenyltransferase activity.
By means of bioinformatic methods of protein modeling and the analysis of molecular interactions, the results of this work reveal, that the PpPRT2 protein probably has catalytic properties related to the synthesis of GPP. If so, its use in a monoterpene production system, based on transgenic microorganisms, might provide a solution to the adverse environmental effects of the monoterpene extraction processes from plants. This ”GreenTech“ system would be more eco-friendly, since it would generate smaller amounts of toxic waste than the current industry’s extraction and purification processes, thus reducing pollution. Moreover, the necessary infrastructure would occupy less space and use less water, saving these limited resources for other uses, such as food production. Finally, the production costs would be reduced, thanks to the low maintenance cost of the smaller infrastructures and the high production yield resulting from the use of genetically modified microorganisms for monoterpene production--ultimately making these processes more profitable.
Keywords: Docking, GPP synthase, Modeling, Pistacia palaestina, PpPRT2.
Book Of Abststracts | Class 20221
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